Cyphering the Complexity of Coronary Artery Disease Using the Syntax Score to Predict Clinical Outcome in Patients With Three-Vessel Lumen Obstruction Undergoing Percutaneous Coronary Intervention

Marco Valgimigli, Patrick Washington Serruys, Keiichi Tsuchida, Sophia Vaina, Marie Angèle Morel, Marcel J. van den Brand, Antonio Colombo, Marie Claude Morice, Keith Dawkins, Bernard de Bruyne, Ran Kornowski, Stefano de Servi, Giulio Guagliumi, J. Wouter Jukema, Frederick W. Mohr, Arie Pieter Kappetein, Kristel Wittebols, Hans Peter Stoll, Eric Boersma, Giovanni Parrinello

Research output: Contribution to journalArticle

Abstract

The Syntax score (SXscore) was recently developed as a comprehensive angiographic scoring system aiming to assist in patient selection and risk stratification of patients with extensive coronary artery disease undergoing contemporary revascularization. A validation of this angiographic classification scheme is lacking. We assessed its predictive value in patients who underwent percutaneous intervention (PCI) for 3-vessel disease and explored its performance in comparison with the modified lesion classification system of the American Heart Association/American College of Cardiology. The SXscore, applied to 1,292 lesions in 306 patients who underwent PCI for 3-vessel disease in the Arterial Revascularization Therapies Study Part II, was 4 to 54.5, and after a median of 370 days (range 274 to 400) predicted the rate of major adverse cardiac and cerebrovascular events (hazard ratio 1.08/U increase, 95% confidence interval 1.05 to 1.11, p

Original languageEnglish
Pages (from-to)1072-1081
Number of pages10
JournalThe American Journal of Cardiology
Volume99
Issue number8
DOIs
Publication statusPublished - Apr 15 2007

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Cyphering the Complexity of Coronary Artery Disease Using the Syntax Score to Predict Clinical Outcome in Patients With Three-Vessel Lumen Obstruction Undergoing Percutaneous Coronary Intervention'. Together they form a unique fingerprint.

  • Cite this

    Valgimigli, M., Serruys, P. W., Tsuchida, K., Vaina, S., Morel, M. A., van den Brand, M. J., Colombo, A., Morice, M. C., Dawkins, K., de Bruyne, B., Kornowski, R., de Servi, S., Guagliumi, G., Jukema, J. W., Mohr, F. W., Kappetein, A. P., Wittebols, K., Stoll, H. P., Boersma, E., & Parrinello, G. (2007). Cyphering the Complexity of Coronary Artery Disease Using the Syntax Score to Predict Clinical Outcome in Patients With Three-Vessel Lumen Obstruction Undergoing Percutaneous Coronary Intervention. The American Journal of Cardiology, 99(8), 1072-1081. https://doi.org/10.1016/j.amjcard.2006.11.062