Cystic echinococcosis of the liver: A primer for hepatologists

Francesca Rinaldi, Enrico Brunetti, Andreas Neumayr, Marcello Maestri, Samuel Goblirsch, Francesca Tamarozzi

Research output: Contribution to journalArticlepeer-review

Abstract

Cystic echinococcosis (CE) is a complex, chronic and neglected disease with a worldwide distribution. The liver is the most frequent location of parasitic cysts. In humans, its clinical spectrum ranges from asymptomatic infection to severe, potentially fatal disease. Four approaches exist in the clinical management of CE: surgery, percutaneous techniques and drug treatment for active cysts, and the "watch and wait" approach for inactive cysts. Allocation of patients to these treatments should be based on cyst stage, size and location, available clinical expertise, and comorbidities. However, clinical decision algorithms, efficacy, relapse rates, and costs have never been properly evaluated. This paper reviews recent advances in classification and diagnosis and the currently available evidence for clinical decision-making in cystic echinococcosis of the liver.

Original languageEnglish
Pages (from-to)293-305
Number of pages13
JournalWorld Journal of Hepatology
Volume6
Issue number5
DOIs
Publication statusPublished - 2014

Keywords

  • Albendazole
  • Clinical management
  • Cystic echinococcosis
  • Diagnosis
  • Follow-up
  • Hydatidosis
  • Percutaneous treatment
  • Surgery
  • Treatment
  • Watch-and-wait

ASJC Scopus subject areas

  • Hepatology

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