Abstract
The cytochemical distribution of dipeptidylaminopeptidase IV (DAP IV) was studied in 5 cases of T lymphoblastic leukaemic lymphoma and 12 cases of acute T lymphoblastic leukaemia, in order to ascertain differences between the enzyme positivity patterns of T cells at different stages of differentiation. Early thymic phenotype cases were almost completely negative; those of intermediate and mature thymic phenotype showed positivity in various percentages of blasts: either a single coarse granule or many coarse and small granules were detected. In mature phenotype cells a particularly intense DAP IV reaction was observed. In conclusion, our findings suggest that DAP IV reaction could be a useful tool for the cytochemical characterization of T acute leukaemia subtypes.
Original language | English |
---|---|
Pages (from-to) | 143-149 |
Number of pages | 7 |
Journal | Haematologia |
Volume | 22 |
Issue number | 3 |
Publication status | Published - 1989 |
ASJC Scopus subject areas
- Hematology