Abstract
Benign proliferative patterns of connective tissue in the dermatofibroma are investigated. Neoplastic fibroblasts are similar to so-called myofibroblasts. However, filaments are the prevalent filamentous component, while microfilaments and microtubules are present in limited amounts. In addition, no junctions are observed between adjacent cells. Typical mast cells and histiocytes are rarely observed. This report adds evidence of the similarity between the neoplastic and inflammatory patterns of fibroblastic proliferation, and suggests that the proliferation of the active fibroblast of the dermatofibroma (viewed as an intermediate cell between the common fibroblast and the myofibroblast) does not lead to the development of a homodynamic system. It also confirms that this tumor may exist in a stable condition.
| Original language | English |
|---|---|
| Pages (from-to) | 113-119 |
| Number of pages | 7 |
| Journal | Annals of Plastic Surgery |
| Volume | 9 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1982 |
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ASJC Scopus subject areas
- Surgery
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Cytofilaments and fibroblast junctions in the benign proliferation of connective tissue. / Donati, L.; Candiani, P.; Virgiliis, G. E.; Sideri, M.; Rainoldi, R.; Le Grazie, C.
In: Annals of Plastic Surgery, Vol. 9, No. 2, 1982, p. 113-119.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cytofilaments and fibroblast junctions in the benign proliferation of connective tissue
AU - Donati, L.
AU - Candiani, P.
AU - Virgiliis, G. E.
AU - Sideri, M.
AU - Rainoldi, R.
AU - Le Grazie, C.
PY - 1982
Y1 - 1982
N2 - Benign proliferative patterns of connective tissue in the dermatofibroma are investigated. Neoplastic fibroblasts are similar to so-called myofibroblasts. However, filaments are the prevalent filamentous component, while microfilaments and microtubules are present in limited amounts. In addition, no junctions are observed between adjacent cells. Typical mast cells and histiocytes are rarely observed. This report adds evidence of the similarity between the neoplastic and inflammatory patterns of fibroblastic proliferation, and suggests that the proliferation of the active fibroblast of the dermatofibroma (viewed as an intermediate cell between the common fibroblast and the myofibroblast) does not lead to the development of a homodynamic system. It also confirms that this tumor may exist in a stable condition.
AB - Benign proliferative patterns of connective tissue in the dermatofibroma are investigated. Neoplastic fibroblasts are similar to so-called myofibroblasts. However, filaments are the prevalent filamentous component, while microfilaments and microtubules are present in limited amounts. In addition, no junctions are observed between adjacent cells. Typical mast cells and histiocytes are rarely observed. This report adds evidence of the similarity between the neoplastic and inflammatory patterns of fibroblastic proliferation, and suggests that the proliferation of the active fibroblast of the dermatofibroma (viewed as an intermediate cell between the common fibroblast and the myofibroblast) does not lead to the development of a homodynamic system. It also confirms that this tumor may exist in a stable condition.
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UR - http://www.scopus.com/inward/citedby.url?scp=0019969848&partnerID=8YFLogxK
U2 - 10.1097/00000637-198208000-00005
DO - 10.1097/00000637-198208000-00005
M3 - Article
VL - 9
SP - 113
EP - 119
JO - Annals of Plastic Surgery
JF - Annals of Plastic Surgery
SN - 0148-7043
IS - 2
ER -