Cytogenetic analysis of transitional cell carcinoma of the bladder. Clinical implications

G. Martorana, C. Giberti, M. de Ferrari, P. Calvi, L. Ottaggio, D. Pescatore

Research output: Contribution to journalArticlepeer-review


Cytogenetic analysis of resected bladder tumors was performed in 30 patients. None of these patients had previous irradiation or chemotherapy. Direct chromosome preparations were made. Of the 30 preparations, 20 had chromosome abnormalities. We have observed a good correlation between the chromosome abnormalities and the stage/grade of the tumors. Patients were followed from 3 to 23 months. During this period, 61% of the patients with noninvasive or submucosal invasive bladder tumors and chromosome abnormalities have had recurrences. The existence of a good correlation between chromosomal abnormalities and the capacity of the neoplasm to recur was confirmed.

Original languageEnglish
Pages (from-to)28-31
Number of pages4
JournalEuropean Urology
Issue number1
Publication statusPublished - 1983

ASJC Scopus subject areas

  • Urology


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