Cytokine-adjuvanted HIV-DNA vaccination strategies

Franco Lori, David B. Weiner, Sandra A. Calarota, Laurene M. Kelly, Julianna Lisziewicz

Research output: Contribution to journalArticlepeer-review

Abstract

This review highlights some of the most common cytokines currently being tested as adjuvants in HIV-1-DNA vaccine regimens. We discuss their use in both the prophylactic and therapeutic setting. Finally, we describe a novel dendritic cell-targeted vaccine candidate for HIV-1 treatment and prevention called DermaVir and explore the combination of the DermaVir technology with the cytokine adjuvants interleukin-7 and interleukin-15.

Original languageEnglish
Pages (from-to)231-238
Number of pages8
JournalSpringer Seminars in Immunopathology
Volume28
Issue number3
DOIs
Publication statusPublished - Nov 2006

Keywords

  • Cytokine
  • DermaVir
  • DNA vaccination
  • HIV

ASJC Scopus subject areas

  • Immunology

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