Abstract
A large body of evidence concerning immunological abnormalities in schizophrenic patients seems to suggest a role of the immune system in the multifactorial pathogenesis of schizophrenia. We investigated the production of various cytokines [interleukin (IL)-2, IL-4, IL-10, interferon (INF)-γ] in drug-free (n = 26) and drug-naive (n = 7) schizophrenic patients and in healthy controls (n = 33). Production of IL-2 and INF-γ was significantly higher (respectively P = 0.021 and P = 0.001) in patients than in controls. These findings provide further evidence that immunological abnormalities are present in some schizophrenic patients.
Original language | English |
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Pages (from-to) | 293-298 |
Number of pages | 6 |
Journal | Schizophrenia Research |
Volume | 47 |
Issue number | 2-3 |
DOIs | |
Publication status | Published - Mar 1 2001 |
ASJC Scopus subject areas
- Psychiatry and Mental health
- Behavioral Neuroscience
- Biological Psychiatry
- Neurology
- Psychology(all)