Cytokines in juvenile rheumatoid arthritis

Research output: Contribution to journalArticle

Abstract

Most data concerning the role of cytokines in chronic arthritides have been obtained in adult rheumatoid arthritis. In this paper we review the available evidence regarding the role of the inflammatory cytokines interleukin-1, interleukin-6, and tumor necrosis factor in juvenile rheumatoid arthritis, focusing in particular on the differences among the various onset types. Results from the analysis of cytokine expression may provide the basis for the use of specific anticytokine treatment. Recent clinical trials in adult rheumatoid arthritis have demonstrated the feasibility and clinical usefulness of these treatments.

Original languageEnglish
Pages (from-to)428-433
Number of pages6
JournalCurrent Opinion in Rheumatology
Volume9
Issue number5
DOIs
Publication statusPublished - 1997

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Juvenile Arthritis
Cytokines
Rheumatoid Arthritis
Interleukin-1
Arthritis
Interleukin-6
Tumor Necrosis Factor-alpha
Clinical Trials

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Cite this

Cytokines in juvenile rheumatoid arthritis. / De Benedetti, Fabrizio; Ravelli, Angelo; Martini, Alberto.

In: Current Opinion in Rheumatology, Vol. 9, No. 5, 1997, p. 428-433.

Research output: Contribution to journalArticle

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