Abstract
Most data concerning the role of cytokines in chronic arthritides have been obtained in adult rheumatoid arthritis. In this paper we review the available evidence regarding the role of the inflammatory cytokines interleukin-1, interleukin-6, and tumor necrosis factor in juvenile rheumatoid arthritis, focusing in particular on the differences among the various onset types. Results from the analysis of cytokine expression may provide the basis for the use of specific anticytokine treatment. Recent clinical trials in adult rheumatoid arthritis have demonstrated the feasibility and clinical usefulness of these treatments.
| Original language | English |
|---|---|
| Pages (from-to) | 428-433 |
| Number of pages | 6 |
| Journal | Current Opinion in Rheumatology |
| Volume | 9 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 1997 |
Fingerprint
ASJC Scopus subject areas
- Immunology
- Rheumatology
Cite this
Cytokines in juvenile rheumatoid arthritis. / De Benedetti, Fabrizio; Ravelli, Angelo; Martini, Alberto.
In: Current Opinion in Rheumatology, Vol. 9, No. 5, 1997, p. 428-433.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cytokines in juvenile rheumatoid arthritis
AU - De Benedetti, Fabrizio
AU - Ravelli, Angelo
AU - Martini, Alberto
PY - 1997
Y1 - 1997
N2 - Most data concerning the role of cytokines in chronic arthritides have been obtained in adult rheumatoid arthritis. In this paper we review the available evidence regarding the role of the inflammatory cytokines interleukin-1, interleukin-6, and tumor necrosis factor in juvenile rheumatoid arthritis, focusing in particular on the differences among the various onset types. Results from the analysis of cytokine expression may provide the basis for the use of specific anticytokine treatment. Recent clinical trials in adult rheumatoid arthritis have demonstrated the feasibility and clinical usefulness of these treatments.
AB - Most data concerning the role of cytokines in chronic arthritides have been obtained in adult rheumatoid arthritis. In this paper we review the available evidence regarding the role of the inflammatory cytokines interleukin-1, interleukin-6, and tumor necrosis factor in juvenile rheumatoid arthritis, focusing in particular on the differences among the various onset types. Results from the analysis of cytokine expression may provide the basis for the use of specific anticytokine treatment. Recent clinical trials in adult rheumatoid arthritis have demonstrated the feasibility and clinical usefulness of these treatments.
UR - http://www.scopus.com/inward/record.url?scp=0030830044&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030830044&partnerID=8YFLogxK
U2 - 10.1097/00002281-199709000-00009
DO - 10.1097/00002281-199709000-00009
M3 - Article
C2 - 9309198
AN - SCOPUS:0030830044
VL - 9
SP - 428
EP - 433
JO - Current Opinion in Rheumatology
JF - Current Opinion in Rheumatology
SN - 1040-8711
IS - 5
ER -