Cytokines, tumour-cell death and immunogenicity: A question of choice

Piero Musiani, Andrea Modesti, Mirella Giovarelli, Federica Cavallo, Guido Forni, Pier Luigi Lollini, Mario P. Colombo

Research output: Contribution to journalArticlepeer-review


How do cytokines released by engineered tumour cells provoke tumour rejection and an immune memory? Is vaccination with tumour cells that have been engineered to secrete cytokines a viable therapeutic perspective? Piero Musiani and colleagues have sought an answer to these questions by transfecting the same tumour with the genes of various cytokines and elucidating the features of the reactions elicited.

Original languageEnglish
Pages (from-to)32-36
Number of pages5
JournalImmunology Today
Issue number1
Publication statusPublished - Jan 1997

ASJC Scopus subject areas

  • Immunology


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