Cytological and immunocytochemical evaluation of thyroid and breast masses in patients with a previous neoplasm: Case reports

T. Pisani, A. Antonaci, N. T. Sinopoli, M. Mottolese, A. Vecchione, M. R. Giovagnoli

Research output: Contribution to journalArticlepeer-review

Abstract

The diagnosis of secondary tumours represents one of the most important fields in the application of fine needle aspiration cytology (FNAC). We studied two patients, one with a history of breast cancer and one with a previous tumour of the thyroid, who showed a second mass, in the thyroid and in the breast, respectively, during follow up. The aim of our study was to evaluate if cytology, performed on FNAC smears, may distinguish a metastatic lesion from a second primary tumour, or if further immunocytochemistry should be performed. Our data demonstrate that, while cytology may be indicative of a second primary tumour, the histotype should be confirmed by immunocytochemical staining.

Original languageEnglish
Pages (from-to)180-185
Number of pages6
JournalCytopathology
Volume10
Issue number3
DOIs
Publication statusPublished - 1999

Keywords

  • Breast cancer
  • Primary tumour
  • Thyroid cancer

ASJC Scopus subject areas

  • Anatomy
  • Cell Biology

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