Cytomegalovirus (AD169) infection in human chondrocyte cell cultures.

A. M. Patti, A. Vulcano, A. Gabriele, C. Della Rocca

Research output: Contribution to journalArticle

Abstract

Human chondrocytes are susceptible to productive human cytomegalovirus (HCMV, AD169 strain) infection. Infection of chondrocytes resulted in pronounced cytopathic effects including cell rounding and aggregation, fusions, and lysis. Immunohistochemical staining reveals that a portion of chondrocytes expressed antigens reactive to monoclonal antibodies against early HCMV proteins. The interaction of HCMV with cartilage cells may be one key for elucidating the etiopathogenesis of articular diseases.

Original languageEnglish
Pages (from-to)177-180
Number of pages4
JournalAnnali di igiene : medicina preventiva e di comunità
Volume19
Issue number3
Publication statusPublished - May 2007

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Cytomegalovirus Infections
Chondrocytes
Cell Culture Techniques
Cell Aggregation
Infection
Cytomegalovirus
Cartilage
Joints
Monoclonal Antibodies
Staining and Labeling
Antigens
Proteins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cytomegalovirus (AD169) infection in human chondrocyte cell cultures. / Patti, A. M.; Vulcano, A.; Gabriele, A.; Della Rocca, C.

In: Annali di igiene : medicina preventiva e di comunità, Vol. 19, No. 3, 05.2007, p. 177-180.

Research output: Contribution to journalArticle

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