Cytomegalovirus DNA retrieval in the inner ear fluids of a congenitally deaf child one month after primary infection: A Case Report

Walter Di Nardo, Paola Cattani, Alessandro Scorpecci, Sara Giannantonio, Sara D'Onghia, Giovanni Fadda, Gaetano Paludetti

Research output: Contribution to journalArticlepeer-review

Abstract

In the present article we report cytomegalovirus (CMV) DNA localization in the inner ear of a 15-month-old deaf boy 1 month after a virologically documented primary infection. CMV DNA retrieval was possible thanks to polymerase chain reaction analysis of the perilymph collected at cochlear implant surgery. To the authors' knowledge this is the first demonstration of CMV persistence in the cochlea of an immunocompetent subject after an acquired infection.

Original languageEnglish
Pages (from-to)828-830
Number of pages3
JournalLaryngoscope
Volume121
Issue number4
DOIs
Publication statusPublished - Apr 2011

Keywords

  • acquired cytomegalovirus infection
  • Cochlear implants
  • GJB2 mutation
  • real-time polymerase chain reaction

ASJC Scopus subject areas

  • Otorhinolaryngology

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