Cytomegalovirus pneumonia in immunocompetent host: Case report and literature review

Research output: Contribution to journalArticle

Abstract

CMV infection is highly prevalent in general population and its clinical picture generally ranges from asymptomatic disease to mononucleosis-like syndrome. While severe life-threatening CMV disease is well documented in certain immunocompromised risk groups, severe infection with symptomatic pneumonia in immunocompetent hosts has been rarely documented.In this paper we describe a case of primary CMV infection, complicated by severe CMV pneumonia in an immunocompetent host, successfully treated with oral valganciclovir. Moreover, we reviewed CMV pneumonia cases in immunocompetent adults reported in the literature.

Original languageEnglish
Pages (from-to)356-359
Number of pages4
JournalJournal of Clinical Virology
Volume55
Issue number4
DOIs
Publication statusPublished - Dec 2012

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Cytomegalovirus
Pneumonia
Infection
Asymptomatic Diseases
Population

Keywords

  • CMV
  • Immunocompetent
  • Pneumonia
  • Therapy
  • Valganciclovir

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

Cite this

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title = "Cytomegalovirus pneumonia in immunocompetent host: Case report and literature review",
abstract = "CMV infection is highly prevalent in general population and its clinical picture generally ranges from asymptomatic disease to mononucleosis-like syndrome. While severe life-threatening CMV disease is well documented in certain immunocompromised risk groups, severe infection with symptomatic pneumonia in immunocompetent hosts has been rarely documented.In this paper we describe a case of primary CMV infection, complicated by severe CMV pneumonia in an immunocompetent host, successfully treated with oral valganciclovir. Moreover, we reviewed CMV pneumonia cases in immunocompetent adults reported in the literature.",
keywords = "CMV, Immunocompetent, Pneumonia, Therapy, Valganciclovir",
author = "Elisabetta Grilli and Vincenzo Galati and Licia Bordi and Fabrizio Taglietti and Nicola Petrosillo",
year = "2012",
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AU - Grilli, Elisabetta

AU - Galati, Vincenzo

AU - Bordi, Licia

AU - Taglietti, Fabrizio

AU - Petrosillo, Nicola

PY - 2012/12

Y1 - 2012/12

N2 - CMV infection is highly prevalent in general population and its clinical picture generally ranges from asymptomatic disease to mononucleosis-like syndrome. While severe life-threatening CMV disease is well documented in certain immunocompromised risk groups, severe infection with symptomatic pneumonia in immunocompetent hosts has been rarely documented.In this paper we describe a case of primary CMV infection, complicated by severe CMV pneumonia in an immunocompetent host, successfully treated with oral valganciclovir. Moreover, we reviewed CMV pneumonia cases in immunocompetent adults reported in the literature.

AB - CMV infection is highly prevalent in general population and its clinical picture generally ranges from asymptomatic disease to mononucleosis-like syndrome. While severe life-threatening CMV disease is well documented in certain immunocompromised risk groups, severe infection with symptomatic pneumonia in immunocompetent hosts has been rarely documented.In this paper we describe a case of primary CMV infection, complicated by severe CMV pneumonia in an immunocompetent host, successfully treated with oral valganciclovir. Moreover, we reviewed CMV pneumonia cases in immunocompetent adults reported in the literature.

KW - CMV

KW - Immunocompetent

KW - Pneumonia

KW - Therapy

KW - Valganciclovir

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