Cytotoxic activities of flavonoid glycoside acetates from Consolida oliveriana

Jesús G. Díaz, Armando J. Carmona, Fernando Torres, José Quintana, Francisco Estévez, Werner Herz

Research output: Contribution to journalArticlepeer-review

Abstract

The flavonoids kaempferol, quercetin, trifolin, hyperoside 2″- and 6″- acetates, 7-glucotrifolin, biorobin and robinin were isolated from the aerial parts of Consolida oliveriana. Their derivatives kaempferol tetraacetate, quercetin pentaacetate, trifolin heptaacetate and hyperoside octaacetate exhibited significant cytotoxicity in vitro against three human cell lines HL-60, U937 and SK-MEL-1 while hyperoside 2″-acetate, hyperoside-6″-acetate, glucotrifolin decaacetate and heptamethyltrifolin were inactive.

Original languageEnglish
Pages (from-to)171-174
Number of pages4
JournalPlanta Medica
Volume74
Issue number2
DOIs
Publication statusPublished - Feb 2008

Keywords

  • Consolida oliveriana
  • Cytoxicity
  • Flavonoid acetates
  • Flavonoids
  • Ranunculaceae

ASJC Scopus subject areas

  • Plant Science
  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

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