Abstract
The authors review the data and knowledge concerning the problem of secondary hormone non responsiveness of advanced prostatic carcinoma after hormone manipulation. They list the mechanisms of this hormone non responsiveness and examine the reasons why the standard chemotherapy is not efficacious as in other solid tumors. The difficulties of administering chemotherapy in patients with hormone escaped prostatic carcinoma are also pointed out (decrease of bone marrow reserve, poor general condition, renal impairment, etc.).
| Original language | English |
|---|---|
| Pages (from-to) | 277-280 |
| Number of pages | 4 |
| Journal | Acta Urologica Italica |
| Volume | 9 |
| Issue number | 5 |
| Publication status | Published - 1995 |
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Keywords
- chemotherapy
- hormone escaped prostatic carcinoma
ASJC Scopus subject areas
- Urology
Cite this
Cytotoxic chemotherapy for advanced hormone-resistant prostate cancer. / Miglietta, L.; Canobbio, L.; Boccardo, F.
In: Acta Urologica Italica, Vol. 9, No. 5, 1995, p. 277-280.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cytotoxic chemotherapy for advanced hormone-resistant prostate cancer
AU - Miglietta, L.
AU - Canobbio, L.
AU - Boccardo, F.
PY - 1995
Y1 - 1995
N2 - The authors review the data and knowledge concerning the problem of secondary hormone non responsiveness of advanced prostatic carcinoma after hormone manipulation. They list the mechanisms of this hormone non responsiveness and examine the reasons why the standard chemotherapy is not efficacious as in other solid tumors. The difficulties of administering chemotherapy in patients with hormone escaped prostatic carcinoma are also pointed out (decrease of bone marrow reserve, poor general condition, renal impairment, etc.).
AB - The authors review the data and knowledge concerning the problem of secondary hormone non responsiveness of advanced prostatic carcinoma after hormone manipulation. They list the mechanisms of this hormone non responsiveness and examine the reasons why the standard chemotherapy is not efficacious as in other solid tumors. The difficulties of administering chemotherapy in patients with hormone escaped prostatic carcinoma are also pointed out (decrease of bone marrow reserve, poor general condition, renal impairment, etc.).
KW - chemotherapy
KW - hormone escaped prostatic carcinoma
UR - http://www.scopus.com/inward/record.url?scp=0028803616&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028803616&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0028803616
VL - 9
SP - 277
EP - 280
JO - Acta Urologica Italica
JF - Acta Urologica Italica
SN - 0394-2511
IS - 5
ER -