Cytotoxicity and cell death: studies on molluscan cells and evolutionary considerations.

D. Monti, S. Salvioli, A. Cossarizza, C. Franceschi, E. Ottaviani

Research output: Contribution to journalArticlepeer-review


In a previous study we demonstrated the presence of NK-like activity in the mollusc Planorbarius corneus. This activity can be ascribed to round hemocytes that have a morphology similar to that of vertebrate lymphocytes. We show here that this NK-like cytotoxicity is evident in serum-free culture medium. Moreover, the type of death induced by molluscan effector cells on their targets is probably similar to that induced by vertebrate effector cells, i.e. apoptosis or programmed cell death, as assessed by the protective effect exerted by 3-aminobenzamide when both types of effector cells were used.

Original languageEnglish
Pages (from-to)287-291
Number of pages5
JournalActa Biologica Hungarica
Issue number1-4
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

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