D-Dimer increase after percutaneous transluminal angioplasty and clinical recurrence after primary revascularization in acute myocardial infarction? A pilot study

D. Prisco, E. Antonucci, S. Fedi, M. Margheri, C. Giglioli, M. Comeglio, A. Lombardi, M. Chioccioli, R. Abbate, G. F. Gensini

Research output: Contribution to journalArticle

Abstract

It has been reported that the increase of plasminogen activator inhibitor-1 activity immediately after elective coronary angioplasty is related to subsequent clinical recurrence in patients with chronic coronary artery disease. The aims of our study were to evaluate the behavior of plasminogen activator inhibitor-1 and D-Dimer after revascularization in acute myocardial infarction patients treated with angioplasty and stenting and if this behavior is predictive of subsequent clinical recurrence. D-Dimer and plasminogen activator inhibitor-1 activity were evaluated in two groups of patients. Group 1 consisted of 54 consecutive patients undergoing primary angioplasty for acute myocardial infarction and Group 2 consisted of 48 patients undergoing elective angioplasty. Patients underwent control coronary angiography only in the case of clinical recurrence and/or positivity of provocative tests. D-Dimer and plasminogen activator inhibitor-1 baseline levels were significantly higher in group 1 than in group 2 (P

Original languageEnglish
Pages (from-to)219-224
Number of pages6
JournalClinical and Experimental Medicine
Volume1
Issue number4
Publication statusPublished - 2001

Keywords

  • Clinical recurrence
  • D-Dimer
  • Percutaneous transluminal angioplasty
  • Plasminogen activator inhibitor-1
  • Primary revascularization
  • Stent

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Clinical Biochemistry

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