Wells' syndrome is a rare disease of uncertain origin clinically characterized by erythematous-edematous plaques which resolve spontaneously after months and recur over many years. Histologically, there is a dermal eosinophilic infiltrate with 'flame figures' and in the older phases a palisading microgranuloma. Blood eosinophilia is often present. We describe a patient affected by Wells' syndrome with lesions localized on the limbs. He had been operated 15 years before for carcinoma of the larynx and he had an episode of urticaria 2 years before. The patient was treated with dapsone 50 mg/day. The lesions healed in 2 months and he had no recurrence. Dapsone should be used in the treatment of Wells' syndrome in lieu of corticosteroids.
|Translated title of the contribution||Dapsone treatment in Well's syndrome. Report of a case|
|Number of pages||3|
|Journal||Giornale Italiano di Dermatologia e Venereologia|
|Publication status||Published - 1994|
ASJC Scopus subject areas