Daptomycin efficacy in the central nervous system of a patient with disseminated methicillin-resistant Staphylococcus aureus infection: A case report

Fabrizio Taglietti, Floriana Campanile, Alessandro Capone, Antonino Di Caro, Elisabetta Grilli, Giulia Stazi, Taschia Bertuccio, Nicola Petrosillo, Stefania Stefani

Research output: Contribution to journalArticle

Abstract

Introduction. Staphylococcus aureus has emerged as a major nosocomial pathogen in the last decades and also represents the second most common pathogen isolated from patients in outpatient settings. Although methicillin-resistant S.aureus infections were traditionally limited to hospitals, community-associated cases of methicillin-resistant S.aureus infections have been reported. In our case, we observed an unexpected event during treatment. Case presentation. A 60-year-old Caucasian man developed fever and multiple muscle and brain abscesses caused by Panton-Valentine leukocidin-negative community-associated methicillin-resistant S. aureus. Conclusion: Although our patient was given antimicrobials active against the isolated methicillin-resistant S. aureus strain, it was only after the introduction of daptomycin that his skin, soft tissue and muscle lesions and also brain manifestations improved.

Original languageEnglish
Article number264
JournalJournal of Medical Case Reports
Volume6
DOIs
Publication statusPublished - 2012

ASJC Scopus subject areas

  • Medicine(all)

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