Data-driven dual-gating for cardiac PET

Kris Thielemans, Paul Schleyer, Paul K. Marsden, Jarmo Teuho, Mika Teras, Valentino Bettinardi, Leon Menezes, Ravindra M. Manjeshwar, Charles W. Stearns

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Image quality in cardiac PET is impaired by both respiratory and cardiac motion. Dual-gating has been proposed as a means to obtain sinograms in various motion states. This data can then be used to produce dual-gated images or as a first step in processing that corrects for one or both types of motion. The gating is normally performed based on external signals such as an ECG signal and a camera or belt for monitoring respiration. However, it could be advantageous if the gating could be performed without ancillary equipment. It has been shown by various authors that it is possible to extract a respiratory signal out of the PET data itself, usually based on low spatial resolution but high time resolution sinograms. Here, we propose an extension to extract the cardiac beating signal as well. We illustrate this using a recently proposed technique that uses PCA to extract multiple signals from the data and show that the cardiac signal can be obtained in a two stage process. The method does not need any image reconstruction and is therefore very fast. We show results on PET patient data using various tracers. We compare the signals extracted using the data-driven method with those obtained with external monitors (including ECG). Our results indicate that in many clinical situations, the data-driven method can achieve equivalent dual-gated images compared to methods that use ancillary equipment.

Original languageEnglish
Title of host publication2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781479960972
DOIs
Publication statusPublished - Mar 10 2016
EventIEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014 - Seattle, United States
Duration: Nov 8 2014Nov 15 2014

Other

OtherIEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014
CountryUnited States
CitySeattle
Period11/8/1411/15/14

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ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

Cite this

Thielemans, K., Schleyer, P., Marsden, P. K., Teuho, J., Teras, M., Bettinardi, V., Menezes, L., Manjeshwar, R. M., & Stearns, C. W. (2016). Data-driven dual-gating for cardiac PET. In 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014 [7430902] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NSSMIC.2014.7430902