Data on cytochrome c oxidase assembly in mice and human fibroblasts or tissues induced by SURF1 defect

Nikola Kovářová, Petr Pecina, Hana Nůsková, Marek Vrbacký, Massimo Zeviani, Tomáš Mráček, Carlo Viscomi, Josef Houštěk

Research output: Contribution to journalArticlepeer-review

Abstract

This paper describes data related to a research article entitled "Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects" [1]. This paper includes data of the quantitative analysis of individual forms of respiratory chain complexes I, III and IV present in SURF1 knockout (SURF1-/-) and control (SURF1+/+) mouse fibroblasts and tissues and in fibroblasts of human control and patients with SURF1 gene mutation. Also it includes data demonstrating response of complex IV, cytochrome c oxidase (COX), to reversible inhibition of mitochondrial translation in SURF1-/- mouse and SURF1 patient fibroblast cell lines.

Original languageEnglish
Pages (from-to)1004-1009
Number of pages6
JournalData in Brief
Volume7
DOIs
Publication statusPublished - Jun 1 2016

Keywords

  • Cytochrome c oxidase
  • Doxycycline
  • Knockout
  • Respiratory chain
  • SURF1

ASJC Scopus subject areas

  • General
  • Education

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