Data on the lipoprotein (a), coronary atherosclerotic burden and vulnerable plaque phenotype in angiographic obstructive coronary artery disease

Giampaolo Niccoli, Diana Chin, Giancarla Scalone, Mario Panebianco, Sofia Abbolito, Nicola Cosentino, Francesca Jacoangeli, Hesham Refaat, Giovanna Gallo, Gerardo Salerno, Massimo Volpe, Filippo Crea, Luciano De Biase

Research output: Contribution to journalArticle

Abstract

Lipoprotein Lp(a) represents an independent risk factor for coronary artery disease (CAD). However, its association with CAD burden and lipid rich plaques prone to rupture in patients with acute coronary syndrome (ACS) still remains unknown. These data aim to investigate the association among serum Lipoprotein(a) (Lpa) levels, coronary atherosclerotic burden and features of culprit plaque in patients with ACS and obstructive CAD. For his reason, a total of 500 ACS patients were enrolled for the angiographic cohort and 51 ACS patients were enrolled for the optical coherence tomography (OCT) cohort. Angiographic CAD severity was assessed by Sullivan score and by Bogaty score including stenosis score and extent index, whereas OCT plaque features were evaluated at the site of the minimal lumen area and along the culprit segment. In the angiographic cohort, Lp(a) was a weak independent predictor of Sullivan score (p30 md/dl) compared to patients with lower Lp(a) levels (

Original languageEnglish
Pages (from-to)1409-1412
Number of pages4
JournalData in Brief
Volume7
DOIs
Publication statusPublished - Jun 1 2016

Keywords

  • Acute coronary syndrome
  • Angiographic analysis
  • Lipoprotein (a)
  • Optical coherence tomography

ASJC Scopus subject areas

  • General
  • Education

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