Abstract
A multiparametric investigation of daytime sleepiness was carried out in 10 patients with a generalized epilepsy treated by phenobarbital, 10 with a cryptogenic partial epilepsy treated by carbamazepine and 10 healthy controls. After a standard ambulatory night-time polysomnography, an objective and subjective estimate of daytime sleepiness was made in each subject by means of the Multiple Sleep Latency Test (MSLT) and visual analogue rating scale (VARS), respectively. Furthermore, a parallel assessment of mood and cognitive tasks involving attention and psychomotor speed was also carried out. The data show that patients on chronic treatment with phenobarbital have a greater daytime sleep tendency and they show a worse score at the digit symbol substitution test, than patients on carbamazepine and healthy controls.
| Original language | English |
|---|---|
| Pages (from-to) | 71-76 |
| Number of pages | 6 |
| Journal | Neurophysiologie Clinique / Clinical Neurophysiology |
| Volume | 23 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1993 |
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ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)
Cite this
Daytime sleepiness in epileptic patients on long-term monotherapy : MSLT, clinical and psychometric assessment. / Manni, R.; Ratti, MT; Galimberti, CA; Morini, R.; Perucca, E.; Tartara, A.
In: Neurophysiologie Clinique / Clinical Neurophysiology, Vol. 23, No. 1, 1993, p. 71-76.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Daytime sleepiness in epileptic patients on long-term monotherapy
T2 - MSLT, clinical and psychometric assessment
AU - Manni, R.
AU - Ratti, MT
AU - Galimberti, CA
AU - Morini, R.
AU - Perucca, E.
AU - Tartara, A.
PY - 1993
Y1 - 1993
N2 - A multiparametric investigation of daytime sleepiness was carried out in 10 patients with a generalized epilepsy treated by phenobarbital, 10 with a cryptogenic partial epilepsy treated by carbamazepine and 10 healthy controls. After a standard ambulatory night-time polysomnography, an objective and subjective estimate of daytime sleepiness was made in each subject by means of the Multiple Sleep Latency Test (MSLT) and visual analogue rating scale (VARS), respectively. Furthermore, a parallel assessment of mood and cognitive tasks involving attention and psychomotor speed was also carried out. The data show that patients on chronic treatment with phenobarbital have a greater daytime sleep tendency and they show a worse score at the digit symbol substitution test, than patients on carbamazepine and healthy controls.
AB - A multiparametric investigation of daytime sleepiness was carried out in 10 patients with a generalized epilepsy treated by phenobarbital, 10 with a cryptogenic partial epilepsy treated by carbamazepine and 10 healthy controls. After a standard ambulatory night-time polysomnography, an objective and subjective estimate of daytime sleepiness was made in each subject by means of the Multiple Sleep Latency Test (MSLT) and visual analogue rating scale (VARS), respectively. Furthermore, a parallel assessment of mood and cognitive tasks involving attention and psychomotor speed was also carried out. The data show that patients on chronic treatment with phenobarbital have a greater daytime sleep tendency and they show a worse score at the digit symbol substitution test, than patients on carbamazepine and healthy controls.
UR - http://www.scopus.com/inward/record.url?scp=0027412770&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027412770&partnerID=8YFLogxK
U2 - 10.1016/S0987-7053(05)80284-9
DO - 10.1016/S0987-7053(05)80284-9
M3 - Article
C2 - 8446074
AN - SCOPUS:0027412770
VL - 23
SP - 71
EP - 76
JO - Neurophysiologie Clinique
JF - Neurophysiologie Clinique
SN - 0987-7053
IS - 1
ER -