TY - JOUR
T1 - De-isolation of patients with pulmonary tuberculosis after start of treatment - clear, unequivocal guidelines are missing
AU - Petersen, Eskild
AU - Khamis, Faryal
AU - Migliori, Giovanni Battista
AU - Bay, Julie Glerup
AU - Marais, Ben
AU - Wejse, Christian
AU - Zumla, Alimuddin
N1 - Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.
PY - 2017/3
Y1 - 2017/3
N2 - The study review guidelines on isolation of patients with tuberculosis, TB, from the World Health Organization, WHO, Centers for Disease Control and Prevention, CDC, and the European Center for Disease Control, ECDC. The review found that unequivocal guidelines for removing patients out of negative-pressure isolation and de-isolation patients from either single rooms or isolation at home is needed. Studies show that the time of effective treatment is the key parameter to follow to determine if patients are contagious to others or not. This means that standard treatment of multi-drug resistant, MDR, TB will not result in the patient being non-infectious. Thus it is important right from the time of diagnosis to know if the patient is infected with MDR TB or not. Thus the early use of molecular techniques to reveal drug susceptibility is important. Clear guidelines stating if patient with microscopy negative sputum no matter infected with fully susceptible or MDR TB, no matter HIV positive or not is needed.
AB - The study review guidelines on isolation of patients with tuberculosis, TB, from the World Health Organization, WHO, Centers for Disease Control and Prevention, CDC, and the European Center for Disease Control, ECDC. The review found that unequivocal guidelines for removing patients out of negative-pressure isolation and de-isolation patients from either single rooms or isolation at home is needed. Studies show that the time of effective treatment is the key parameter to follow to determine if patients are contagious to others or not. This means that standard treatment of multi-drug resistant, MDR, TB will not result in the patient being non-infectious. Thus it is important right from the time of diagnosis to know if the patient is infected with MDR TB or not. Thus the early use of molecular techniques to reveal drug susceptibility is important. Clear guidelines stating if patient with microscopy negative sputum no matter infected with fully susceptible or MDR TB, no matter HIV positive or not is needed.
KW - Antitubercular Agents
KW - Female
KW - Humans
KW - Internationality
KW - Male
KW - Patient Isolation
KW - Practice Guidelines as Topic
KW - Tuberculosis, Pulmonary
KW - United States
KW - World Health Organization
KW - Journal Article
KW - Review
U2 - 10.1016/j.ijid.2017.01.029
DO - 10.1016/j.ijid.2017.01.029
M3 - Review article
C2 - 28163167
VL - 56
SP - 34
EP - 38
JO - International Journal of Infectious Diseases
JF - International Journal of Infectious Diseases
SN - 1201-9712
ER -