De novo (15;21) unbalanced translocation of paternal origin in a girl with Preder Willi syndrome

C. Cuoco, M. P. Bicocchi, D. Granata, P. Mezzano, G. Serra

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We describe a 3-month-old girl with Prader-Willi syndrome and a de novo unbalanced karyotype 45,XX,t(15;21)(q13;q22.3). This rearrangement, resulting in monosomy for the pericentromeric region of chromosome 15 and a virtual monosomy for the 21q distal band, had a paternal origin as demonstrated by Q and NOR staining.

Original languageEnglish
Pages (from-to)62-64
Number of pages3
JournalAmerican Journal of Medical Genetics
Volume37
Issue number1
DOIs
Publication statusPublished - 1990

Fingerprint

Monosomy
Prader-Willi Syndrome
Chromosomes, Human, Pair 15
Karyotype
Staining and Labeling

Keywords

  • chromosome 15
  • unbalanced translocation

ASJC Scopus subject areas

  • Genetics(clinical)

Cite this

De novo (15;21) unbalanced translocation of paternal origin in a girl with Preder Willi syndrome. / Cuoco, C.; Bicocchi, M. P.; Granata, D.; Mezzano, P.; Serra, G.

In: American Journal of Medical Genetics, Vol. 37, No. 1, 1990, p. 62-64.

Research output: Contribution to journalArticle

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AU - Serra, G.

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