De Novo, Progressed, and Neglected Metastatic Castration-Sensitive Prostate Cancer: Is One Therapy Fit for All?

Roberto Iacovelli; Chiara Ciccarese; Claudia Mosillo; Giampaolo Tortora

doi:10.1016/j.clgc.2018.07.014

De Novo, Progressed, and Neglected Metastatic Castration-Sensitive Prostate Cancer: Is One Therapy Fit for All?

Roberto Iacovelli, Chiara Ciccarese, Claudia Mosillo, Giampaolo Tortora

IRCCS Fondazione Policlinico Universitario A. Gemelli

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Patients who receive a diagnosis of metastatic castration-sensitive prostate cancer (CSPC) have different phenotypes of disease. Some of them have de novo CSPC, but others receive a late diagnosis, and still others underwent prostatectomy several years before the diagnosis of metastases. We analyze the presence of these differences in recent clinical trials in CSPC and assess the possible impact on their results.

Original language	English
Pages (from-to)	482-484
Number of pages	3
Journal	Clinical Genitourinary Cancer
Volume	16
Issue number	6
DOIs	https://doi.org/10.1016/j.clgc.2018.07.014
Publication status	Published - Dec 1 2018

Keywords

Abiraterone
CSPC
Docetaxel
HSPC
Prognosis

ASJC Scopus subject areas

Oncology
Urology

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10.1016/j.clgc.2018.07.014

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title = "De Novo, Progressed, and Neglected Metastatic Castration-Sensitive Prostate Cancer: Is One Therapy Fit for All?",

abstract = "Patients who receive a diagnosis of metastatic castration-sensitive prostate cancer (CSPC) have different phenotypes of disease. Some of them have de novo CSPC, but others receive a late diagnosis, and still others underwent prostatectomy several years before the diagnosis of metastases. We analyze the presence of these differences in recent clinical trials in CSPC and assess the possible impact on their results.",

keywords = "Abiraterone, CSPC, Docetaxel, HSPC, Prognosis",

author = "Roberto Iacovelli and Chiara Ciccarese and Claudia Mosillo and Giampaolo Tortora",

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T2 - Is One Therapy Fit for All?

AU - Iacovelli, Roberto

AU - Ciccarese, Chiara

AU - Mosillo, Claudia

AU - Tortora, Giampaolo

PY - 2018/12/1

Y1 - 2018/12/1

N2 - Patients who receive a diagnosis of metastatic castration-sensitive prostate cancer (CSPC) have different phenotypes of disease. Some of them have de novo CSPC, but others receive a late diagnosis, and still others underwent prostatectomy several years before the diagnosis of metastases. We analyze the presence of these differences in recent clinical trials in CSPC and assess the possible impact on their results.

AB - Patients who receive a diagnosis of metastatic castration-sensitive prostate cancer (CSPC) have different phenotypes of disease. Some of them have de novo CSPC, but others receive a late diagnosis, and still others underwent prostatectomy several years before the diagnosis of metastases. We analyze the presence of these differences in recent clinical trials in CSPC and assess the possible impact on their results.

KW - Abiraterone

KW - CSPC

KW - Docetaxel

KW - HSPC

KW - Prognosis

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DO - 10.1016/j.clgc.2018.07.014

M3 - Comment/debate

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AN - SCOPUS:85051639103

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EP - 484

JO - Clinical Genitourinary Cancer

JF - Clinical Genitourinary Cancer

SN - 1558-7673

IS - 6

ER -

De Novo, Progressed, and Neglected Metastatic Castration-Sensitive Prostate Cancer: Is One Therapy Fit for All?

Abstract

Keywords

ASJC Scopus subject areas

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