Abstract
Total cases of fatal asthma in the occupational setting reported in the literature are reviewed and the case of a 39-year-old foundry worker who died at work is described. A diagnosis of occupational asthma induced by diphenylmethane diisocyanate (MDI) had been assessed 5 years in advance through a 0.005 ppm exposure inhalation challenge. Postmortem microscopic examination of the lung showed epithelial desquamation, eosinophilic/neutrophilic infiltration of the mucosa, dilatation of bronchial vessels, edema, hypertrophy and disarray of smooth muscle. Fatal asthma attack in a MDI-sensitized individual, to our knowledge, has not been previously described.
| Original language | English |
|---|---|
| Pages (from-to) | 111-113 |
| Number of pages | 3 |
| Journal | Respiration |
| Volume | 64 |
| Issue number | 1 |
| Publication status | Published - Jan 1997 |
Keywords
- Asthma mortality
- Fatal outcome
- Isocyanates
- Occupational asthma
ASJC Scopus subject areas
- Physiology
- Pulmonary and Respiratory Medicine
Fingerprint Dive into the research topics of 'Death due to asthma at workplace in a diphenylmethane diisocyanate-sensitized subject'. Together they form a unique fingerprint.
Cite this
Carino, M., Aliani, M., Licitra, C., Sarno, N., & Ioli, F. (1997). Death due to asthma at workplace in a diphenylmethane diisocyanate-sensitized subject. Respiration, 64(1), 111-113.