Decisional flow with a scoring system to start platelet-lowering treatment in patients with essential thrombocythemia: Long-term results

Roberto Latagliata, Angela Rago, Antonio Spadea, Cristina Santoro, Ida Carmosino, Massimo Breccia, Laura Napoleone, Angelo Fama, Francesca Biondo, Paola Volpicelli, Federico Vozella, Caterina Stefanizzi, Maria Concetta Petti, Giuliana Alimena, Maria Gabriella Mazzucconi

Research output: Contribution to journalArticlepeer-review

Abstract

We prospectively tested, at diagnosis in essential thrombocythemia (ET) patients with no clear indication to platelet (PLT)-lowering treatment, a scoring system based on age, PLT level, cardiovascular diseases, previous thrombotic events, smoking and dysmetabolic diseases. From 04/92 to 03/98, 168 consecutive patients were enrolled. Hydroxyurea (HU) was started at diagnosis in 32 "symptomatic" patients and in 33 patients aged >70 years. The remaining 103 patients ("asymptomatic" and aged

Original languageEnglish
Pages (from-to)486-491
Number of pages6
JournalInternational Journal of Hematology
Volume90
Issue number4
DOIs
Publication statusPublished - 2009

Keywords

  • Essential thrombocythemia
  • Hydroxyurea
  • Thrombotic complications

ASJC Scopus subject areas

  • Hematology

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