Decrease in N-acetyl-L-aspartic acid in brain of myodystrophic mice

F. Marcucci, L. Colombo, G. De Ponte, E. Mussini

Research output: Contribution to journalArticlepeer-review

Abstract

Brain tissue from myodystrophic mice (male 129/Rej-dy and female 129 B6F1/J-dy) was examined to determine whether CNS abnormalities accompany the known muscular defects. Brain N-acetyl-L-aspartate, aspartate, and glutamate were significantly lower than in brain from control mice. These amino acids are only slightly reduced in brain of female dystrophic mice.

Original languageEnglish
Pages (from-to)1484-1486
Number of pages3
JournalJournal of Neurochemistry
Volume43
Issue number5
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Biochemistry
  • Cellular and Molecular Neuroscience

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