Abstract
Since 5-HT appears to be involved in the regulation of food intake in various animal species as well as in the anorectic activity of fenfluramine, it was speculated that quipazine might affect the food intake of rats as a consequence of its ability to mimic 5-HT activity. The present experiments were undertaken in an attempt to verify this hypothesis. The present data further support the hypothesis for an involvement of central 5-HT in the mechanisms regulating food intake and suggest that quipazine may be an additional useful tool to investigate such mechanisms.
| Original language | English |
|---|---|
| Pages (from-to) | 53-54 |
| Number of pages | 2 |
| Journal | Journal of Pharmacy and Pharmacology |
| Volume | 29 |
| Issue number | 1 |
| Publication status | Published - 1977 |
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ASJC Scopus subject areas
- Pharmaceutical Science
- Pharmacology
Cite this
Decrease of food intake by quipazine in the rat : relation to serotoninergic receptor stimulation. / Samanin, R.; Bendotti, C.; Miranda, F.; Garattini, S.
In: Journal of Pharmacy and Pharmacology, Vol. 29, No. 1, 1977, p. 53-54.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Decrease of food intake by quipazine in the rat
T2 - relation to serotoninergic receptor stimulation
AU - Samanin, R.
AU - Bendotti, C.
AU - Miranda, F.
AU - Garattini, S.
PY - 1977
Y1 - 1977
N2 - Since 5-HT appears to be involved in the regulation of food intake in various animal species as well as in the anorectic activity of fenfluramine, it was speculated that quipazine might affect the food intake of rats as a consequence of its ability to mimic 5-HT activity. The present experiments were undertaken in an attempt to verify this hypothesis. The present data further support the hypothesis for an involvement of central 5-HT in the mechanisms regulating food intake and suggest that quipazine may be an additional useful tool to investigate such mechanisms.
AB - Since 5-HT appears to be involved in the regulation of food intake in various animal species as well as in the anorectic activity of fenfluramine, it was speculated that quipazine might affect the food intake of rats as a consequence of its ability to mimic 5-HT activity. The present experiments were undertaken in an attempt to verify this hypothesis. The present data further support the hypothesis for an involvement of central 5-HT in the mechanisms regulating food intake and suggest that quipazine may be an additional useful tool to investigate such mechanisms.
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UR - http://www.scopus.com/inward/citedby.url?scp=0017340750&partnerID=8YFLogxK
M3 - Article
C2 - 13187
AN - SCOPUS:0017340750
VL - 29
SP - 53
EP - 54
JO - Journal of Pharmacy and Pharmacology
JF - Journal of Pharmacy and Pharmacology
SN - 0022-3573
IS - 1
ER -