Decrease of food intake by quipazine in the rat: relation to serotoninergic receptor stimulation

R. Samanin, C. Bendotti, F. Miranda, S. Garattini

Research output: Contribution to journalArticlepeer-review

Abstract

Since 5-HT appears to be involved in the regulation of food intake in various animal species as well as in the anorectic activity of fenfluramine, it was speculated that quipazine might affect the food intake of rats as a consequence of its ability to mimic 5-HT activity. The present experiments were undertaken in an attempt to verify this hypothesis. The present data further support the hypothesis for an involvement of central 5-HT in the mechanisms regulating food intake and suggest that quipazine may be an additional useful tool to investigate such mechanisms.

Original languageEnglish
Pages (from-to)53-54
Number of pages2
JournalJournal of Pharmacy and Pharmacology
Volume29
Issue number1
Publication statusPublished - 1977

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Pharmacology

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