Antithrombin III activity was moderately but significantly decreased in insulin dependent diabetics (p <0.005), while no difference has been found between the diabetic (n = 25) and control groups (n = 22) in antithrombin III plasma concentration. Moreover, antithrombin III activity was inversely correlated with glycosylated plasma proteins (r = -0.57; p <0.01). These data show that in diabetes there is a depressed biological activity of antithrombin III and suggest that this reflects nonenzymatic glycosylation of antithrombin III protein.
|Number of pages||2|
|Journal||Thrombosis and Haemostasis|
|Publication status||Published - 1983|
ASJC Scopus subject areas