Decreased EMG inhibition following electrical stimulation over muscle tendons in myopathies

A. Priori, C. Cinnante, A. Pesenti, A. Gallanti, A. Cappellari, G. Scarlato, S. Barbieri

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: To assess the central EMG inhibitory action of tendon afferent input in muscle diseases. Methods: The EMG inhibition elicited by electrical stimulation over muscle tendons was tested in 13 healthy voluntary subjects and 8 patients who had a primary muscle disease with a mild force deficit. Electrical stimuli were delivered to the tendon of the extensor carpi radialis muscle at the wrist during tonic voluntary isometric contraction at 50% of the maximum EMG level. The EMG signal was recorded by surface electrodes over the extensor carpi radialis muscle. Results: The prestimulus background EMG level was reduced in 7 out 8 of the patients. Both groups had the same phases of EMG modulation following tendon stimulation (TE1, TI1, TE2) and their latency and amplitude did not differ significantly. Conversely, the area of TI1 was significantly larger (i.e. the inhibition decreased) in patients ([mean ± SD] absolute area: controls = 4.1 ± 1.6 mVms, patients = 6.9 ± 2.9 mVms, P <0.05). Conclusions: In muscle dysfunction there are serial 'upstream' changes of central inhibitory systems, probably to maximize the residual muscle power of the affected muscle.

Original languageEnglish
Pages (from-to)1931-1935
Number of pages5
JournalClinical Neurophysiology
Volume112
Issue number10
DOIs
Publication statusPublished - 2001

Fingerprint

Muscular Diseases
Tendons
Electric Stimulation
Muscles
Isometric Contraction
Wrist
Healthy Volunteers
Electrodes

Keywords

  • Human motor control
  • Myopathy
  • Tendon inhibition
  • Voluntary muscle contraction

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Sensory Systems

Cite this

Decreased EMG inhibition following electrical stimulation over muscle tendons in myopathies. / Priori, A.; Cinnante, C.; Pesenti, A.; Gallanti, A.; Cappellari, A.; Scarlato, G.; Barbieri, S.

In: Clinical Neurophysiology, Vol. 112, No. 10, 2001, p. 1931-1935.

Research output: Contribution to journalArticle

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AU - Priori, A.

AU - Cinnante, C.

AU - Pesenti, A.

AU - Gallanti, A.

AU - Cappellari, A.

AU - Scarlato, G.

AU - Barbieri, S.

PY - 2001

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N2 - Objective: To assess the central EMG inhibitory action of tendon afferent input in muscle diseases. Methods: The EMG inhibition elicited by electrical stimulation over muscle tendons was tested in 13 healthy voluntary subjects and 8 patients who had a primary muscle disease with a mild force deficit. Electrical stimuli were delivered to the tendon of the extensor carpi radialis muscle at the wrist during tonic voluntary isometric contraction at 50% of the maximum EMG level. The EMG signal was recorded by surface electrodes over the extensor carpi radialis muscle. Results: The prestimulus background EMG level was reduced in 7 out 8 of the patients. Both groups had the same phases of EMG modulation following tendon stimulation (TE1, TI1, TE2) and their latency and amplitude did not differ significantly. Conversely, the area of TI1 was significantly larger (i.e. the inhibition decreased) in patients ([mean ± SD] absolute area: controls = 4.1 ± 1.6 mVms, patients = 6.9 ± 2.9 mVms, P <0.05). Conclusions: In muscle dysfunction there are serial 'upstream' changes of central inhibitory systems, probably to maximize the residual muscle power of the affected muscle.

AB - Objective: To assess the central EMG inhibitory action of tendon afferent input in muscle diseases. Methods: The EMG inhibition elicited by electrical stimulation over muscle tendons was tested in 13 healthy voluntary subjects and 8 patients who had a primary muscle disease with a mild force deficit. Electrical stimuli were delivered to the tendon of the extensor carpi radialis muscle at the wrist during tonic voluntary isometric contraction at 50% of the maximum EMG level. The EMG signal was recorded by surface electrodes over the extensor carpi radialis muscle. Results: The prestimulus background EMG level was reduced in 7 out 8 of the patients. Both groups had the same phases of EMG modulation following tendon stimulation (TE1, TI1, TE2) and their latency and amplitude did not differ significantly. Conversely, the area of TI1 was significantly larger (i.e. the inhibition decreased) in patients ([mean ± SD] absolute area: controls = 4.1 ± 1.6 mVms, patients = 6.9 ± 2.9 mVms, P <0.05). Conclusions: In muscle dysfunction there are serial 'upstream' changes of central inhibitory systems, probably to maximize the residual muscle power of the affected muscle.

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