Decreased hippocampal BDNF expression after acute systemic injection of quinpirole

Fabio Fumagalli, Raffaella Santero, Massimo Gennarelli, Giorgio Racagni, Marco Andrea Riva

Research output: Contribution to journalArticle

Abstract

We report that acute quinpirole injection reduces BDNF mRNA levels in the rat hippocampus both at 2 and 6 h after the administration. These results suggest that the neurotrophin expression may be inhibited by situations involving dopaminergic overactivity.

Original languageEnglish
Pages (from-to)954-957
Number of pages4
JournalNeuropharmacology
Volume40
Issue number7
DOIs
Publication statusPublished - 2001

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Keywords

  • Dopamine D2 receptors
  • Neurotrophin

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience
  • Drug Discovery
  • Pharmacology

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