Decreased plasma levels of darunavir/ritonavir in a vertically infected pregnant woman carrying multiclass-resistant HIV type-1

Carmela Pinnetti, Enrica Tamburrini, Enzo Ragazzoni, Andrea De Luca, Pierluigi Navarra

Research output: Contribution to journalArticlepeer-review

Abstract

We report a case of a vertically infected woman treated with darunavir/ritonavir plus a standard backbone before pregnancy. The analysis of darunavir/ritonavir concentrations in peripheral maternal plasma throughout pregnancy, as well as in umbilical cord blood at delivery, showed low levels of darunavir in the mother and limited transfer across the placenta.

Original languageEnglish
Pages (from-to)127-129
Number of pages3
JournalAntiviral Therapy
Volume15
Issue number1
DOIs
Publication statusPublished - 2010

ASJC Scopus subject areas

  • Infectious Diseases
  • Pharmacology (medical)
  • Pharmacology

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