Decreased plasma levels of darunavir/ritonavir in a vertically infected pregnant woman carrying multiclass-resistant HIV type-1

Carmela Pinnetti; Enrica Tamburrini; Enzo Ragazzoni; Andrea De Luca; Pierluigi Navarra

doi:10.3851/IMP1473

Decreased plasma levels of darunavir/ritonavir in a vertically infected pregnant woman carrying multiclass-resistant HIV type-1

Carmela Pinnetti, Enrica Tamburrini, Enzo Ragazzoni, Andrea De Luca, Pierluigi Navarra

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research output: Contribution to journal › Article › peer-review

Abstract

We report a case of a vertically infected woman treated with darunavir/ritonavir plus a standard backbone before pregnancy. The analysis of darunavir/ritonavir concentrations in peripheral maternal plasma throughout pregnancy, as well as in umbilical cord blood at delivery, showed low levels of darunavir in the mother and limited transfer across the placenta.

Original language	English
Pages (from-to)	127-129
Number of pages	3
Journal	Antiviral Therapy
Volume	15
Issue number	1
DOIs	https://doi.org/10.3851/IMP1473
Publication status	Published - 2010

ASJC Scopus subject areas

Infectious Diseases
Pharmacology (medical)
Pharmacology

Access to Document

10.3851/IMP1473

Fingerprint Dive into the research topics of 'Decreased plasma levels of darunavir/ritonavir in a vertically infected pregnant woman carrying multiclass-resistant HIV type-1'. Together they form a unique fingerprint.

Cite this

@article{4b2259d5ad344608a01b813f34574ac5,

title = "Decreased plasma levels of darunavir/ritonavir in a vertically infected pregnant woman carrying multiclass-resistant HIV type-1",

abstract = "We report a case of a vertically infected woman treated with darunavir/ritonavir plus a standard backbone before pregnancy. The analysis of darunavir/ritonavir concentrations in peripheral maternal plasma throughout pregnancy, as well as in umbilical cord blood at delivery, showed low levels of darunavir in the mother and limited transfer across the placenta.",

author = "Carmela Pinnetti and Enrica Tamburrini and Enzo Ragazzoni and {De Luca}, Andrea and Pierluigi Navarra",

year = "2010",

doi = "10.3851/IMP1473",

language = "English",

volume = "15",

pages = "127--129",

journal = "Antiviral Therapy",

issn = "1359-6535",

publisher = "International Medical Press Ltd",

number = "1",

}

TY - JOUR

T1 - Decreased plasma levels of darunavir/ritonavir in a vertically infected pregnant woman carrying multiclass-resistant HIV type-1

AU - Pinnetti, Carmela

AU - Tamburrini, Enrica

AU - Ragazzoni, Enzo

AU - De Luca, Andrea

AU - Navarra, Pierluigi

PY - 2010

Y1 - 2010

N2 - We report a case of a vertically infected woman treated with darunavir/ritonavir plus a standard backbone before pregnancy. The analysis of darunavir/ritonavir concentrations in peripheral maternal plasma throughout pregnancy, as well as in umbilical cord blood at delivery, showed low levels of darunavir in the mother and limited transfer across the placenta.

AB - We report a case of a vertically infected woman treated with darunavir/ritonavir plus a standard backbone before pregnancy. The analysis of darunavir/ritonavir concentrations in peripheral maternal plasma throughout pregnancy, as well as in umbilical cord blood at delivery, showed low levels of darunavir in the mother and limited transfer across the placenta.

UR - http://www.scopus.com/inward/record.url?scp=77949384065&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77949384065&partnerID=8YFLogxK

U2 - 10.3851/IMP1473

DO - 10.3851/IMP1473

M3 - Article

C2 - 20167999

AN - SCOPUS:77949384065

VL - 15

SP - 127

EP - 129

JO - Antiviral Therapy

JF - Antiviral Therapy

SN - 1359-6535

IS - 1

ER -