Decreased sympathetic inhibition in gastroesophageal reflux disease

S. M A Campo, A. Capria, F. Antonucci, G. Martino, A. Ciamei, P. M. Rossini, E. Bologna, D. Cannata

Research output: Contribution to journalArticle

Abstract

This study was undertaken to evaluate autonomic nervous system function in patients with gastroesophageal reflux disease. Based on clinical criteria, 28 consecutive patients with no history of heart, metabolic, or neurologic disease (mean age 41 y, range 20-62 y) reporting with upper gastrointestinal symptoms typical of gastroesophageal reflux underwent esophageal manometry, ambulatory 24-hour pH study with electrocardiographic monitoring, power spectral analysis of heart rate variability, and cardiovascular tests. Twelve healthy subjects served as controls. A positive result of prolonged esophageal pH study (pH in the distal esophagus less than 4, lasting more than 4.2% of recording time) was observed in 21 patients (reflux group); seven patients were categorized in the nonreflux group. No patient showed arrhythmias or any correlation between heart rate variability changes during electrocardiographic monitoring and episodes of reflux (pH less than 4, lasting more than 5 minutes). A decrease of sympathetic function occurred only in the reflux group (p

Original languageEnglish
Pages (from-to)45-51
Number of pages7
JournalClinical Autonomic Research
Volume11
Issue number1
Publication statusPublished - 2001

Fingerprint

Gastroesophageal Reflux
Heart Rate
Autonomic Nervous System
Metabolic Diseases
Manometry
Nervous System Diseases
Esophagus
Cardiac Arrhythmias
Heart Diseases
Healthy Volunteers

Keywords

  • Autonomic nervous system
  • Gastroesophageal reflux

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Campo, S. M. A., Capria, A., Antonucci, F., Martino, G., Ciamei, A., Rossini, P. M., ... Cannata, D. (2001). Decreased sympathetic inhibition in gastroesophageal reflux disease. Clinical Autonomic Research, 11(1), 45-51.

Decreased sympathetic inhibition in gastroesophageal reflux disease. / Campo, S. M A; Capria, A.; Antonucci, F.; Martino, G.; Ciamei, A.; Rossini, P. M.; Bologna, E.; Cannata, D.

In: Clinical Autonomic Research, Vol. 11, No. 1, 2001, p. 45-51.

Research output: Contribution to journalArticle

Campo, SMA, Capria, A, Antonucci, F, Martino, G, Ciamei, A, Rossini, PM, Bologna, E & Cannata, D 2001, 'Decreased sympathetic inhibition in gastroesophageal reflux disease', Clinical Autonomic Research, vol. 11, no. 1, pp. 45-51.
Campo SMA, Capria A, Antonucci F, Martino G, Ciamei A, Rossini PM et al. Decreased sympathetic inhibition in gastroesophageal reflux disease. Clinical Autonomic Research. 2001;11(1):45-51.
Campo, S. M A ; Capria, A. ; Antonucci, F. ; Martino, G. ; Ciamei, A. ; Rossini, P. M. ; Bologna, E. ; Cannata, D. / Decreased sympathetic inhibition in gastroesophageal reflux disease. In: Clinical Autonomic Research. 2001 ; Vol. 11, No. 1. pp. 45-51.
@article{d4195cb60d0248269b850eafefc9b8a9,
title = "Decreased sympathetic inhibition in gastroesophageal reflux disease",
abstract = "This study was undertaken to evaluate autonomic nervous system function in patients with gastroesophageal reflux disease. Based on clinical criteria, 28 consecutive patients with no history of heart, metabolic, or neurologic disease (mean age 41 y, range 20-62 y) reporting with upper gastrointestinal symptoms typical of gastroesophageal reflux underwent esophageal manometry, ambulatory 24-hour pH study with electrocardiographic monitoring, power spectral analysis of heart rate variability, and cardiovascular tests. Twelve healthy subjects served as controls. A positive result of prolonged esophageal pH study (pH in the distal esophagus less than 4, lasting more than 4.2{\%} of recording time) was observed in 21 patients (reflux group); seven patients were categorized in the nonreflux group. No patient showed arrhythmias or any correlation between heart rate variability changes during electrocardiographic monitoring and episodes of reflux (pH less than 4, lasting more than 5 minutes). A decrease of sympathetic function occurred only in the reflux group (p",
keywords = "Autonomic nervous system, Gastroesophageal reflux",
author = "Campo, {S. M A} and A. Capria and F. Antonucci and G. Martino and A. Ciamei and Rossini, {P. M.} and E. Bologna and D. Cannata",
year = "2001",
language = "English",
volume = "11",
pages = "45--51",
journal = "Clinical Autonomic Research",
issn = "0959-9851",
publisher = "D. Steinkopff-Verlag",
number = "1",

}

TY - JOUR

T1 - Decreased sympathetic inhibition in gastroesophageal reflux disease

AU - Campo, S. M A

AU - Capria, A.

AU - Antonucci, F.

AU - Martino, G.

AU - Ciamei, A.

AU - Rossini, P. M.

AU - Bologna, E.

AU - Cannata, D.

PY - 2001

Y1 - 2001

N2 - This study was undertaken to evaluate autonomic nervous system function in patients with gastroesophageal reflux disease. Based on clinical criteria, 28 consecutive patients with no history of heart, metabolic, or neurologic disease (mean age 41 y, range 20-62 y) reporting with upper gastrointestinal symptoms typical of gastroesophageal reflux underwent esophageal manometry, ambulatory 24-hour pH study with electrocardiographic monitoring, power spectral analysis of heart rate variability, and cardiovascular tests. Twelve healthy subjects served as controls. A positive result of prolonged esophageal pH study (pH in the distal esophagus less than 4, lasting more than 4.2% of recording time) was observed in 21 patients (reflux group); seven patients were categorized in the nonreflux group. No patient showed arrhythmias or any correlation between heart rate variability changes during electrocardiographic monitoring and episodes of reflux (pH less than 4, lasting more than 5 minutes). A decrease of sympathetic function occurred only in the reflux group (p

AB - This study was undertaken to evaluate autonomic nervous system function in patients with gastroesophageal reflux disease. Based on clinical criteria, 28 consecutive patients with no history of heart, metabolic, or neurologic disease (mean age 41 y, range 20-62 y) reporting with upper gastrointestinal symptoms typical of gastroesophageal reflux underwent esophageal manometry, ambulatory 24-hour pH study with electrocardiographic monitoring, power spectral analysis of heart rate variability, and cardiovascular tests. Twelve healthy subjects served as controls. A positive result of prolonged esophageal pH study (pH in the distal esophagus less than 4, lasting more than 4.2% of recording time) was observed in 21 patients (reflux group); seven patients were categorized in the nonreflux group. No patient showed arrhythmias or any correlation between heart rate variability changes during electrocardiographic monitoring and episodes of reflux (pH less than 4, lasting more than 5 minutes). A decrease of sympathetic function occurred only in the reflux group (p

KW - Autonomic nervous system

KW - Gastroesophageal reflux

UR - http://www.scopus.com/inward/record.url?scp=0034753715&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034753715&partnerID=8YFLogxK

M3 - Article

C2 - 11503951

AN - SCOPUS:0034753715

VL - 11

SP - 45

EP - 51

JO - Clinical Autonomic Research

JF - Clinical Autonomic Research

SN - 0959-9851

IS - 1

ER -