Abstract
We describe the design, realization and basic tests of a prototype Cone-Beam Breast Computed Tomography (CBBCT) scanner, combined with a SPECT head consisting of a compact pinhole gamma camera based on a photon counting CdTe hybrid pixel detector. The instrument features a 40 μm focal spot X-ray tube, a 50 μm pitch flat panel detector and a 1-mm-thick, 55 μm pitch CdTe pixel detector. Preliminary imaging tests of the separate CT and gamma-ray units are presented showing a resolution in CT of 3.2 mm-1 at a radial distance of 50 mm from the rotation axis and that the 5 and 8 mm hot masses (99mTc labeled with a 15:1 activity ratio with respect to the background) can be detected in planar gamma-ray imaging with a contrast-to-noise ratio of about 4.
| Original language | English |
|---|---|
| Pages (from-to) | 350-356 |
| Number of pages | 7 |
| Journal | Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment |
| Volume | 629 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Feb 11 2011 |
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Keywords
- Breast computed tomographySPECT/CT multimodality imaging
ASJC Scopus subject areas
- Instrumentation
- Nuclear and High Energy Physics
Cite this
Dedicated scanner for laboratory investigations on cone-beam CT/SPECT imaging of the breast. / Mettivier, Giovanni; Russo, Paolo; Cesarelli, Mario; Ospizio, Roberto; Passeggio, Giuseppe; Roscilli, Lorenzo; Pontoriere, Giuseppe; Rocco, Raffaele.
In: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 629, No. 1, 11.02.2011, p. 350-356.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dedicated scanner for laboratory investigations on cone-beam CT/SPECT imaging of the breast
AU - Mettivier, Giovanni
AU - Russo, Paolo
AU - Cesarelli, Mario
AU - Ospizio, Roberto
AU - Passeggio, Giuseppe
AU - Roscilli, Lorenzo
AU - Pontoriere, Giuseppe
AU - Rocco, Raffaele
PY - 2011/2/11
Y1 - 2011/2/11
N2 - We describe the design, realization and basic tests of a prototype Cone-Beam Breast Computed Tomography (CBBCT) scanner, combined with a SPECT head consisting of a compact pinhole gamma camera based on a photon counting CdTe hybrid pixel detector. The instrument features a 40 μm focal spot X-ray tube, a 50 μm pitch flat panel detector and a 1-mm-thick, 55 μm pitch CdTe pixel detector. Preliminary imaging tests of the separate CT and gamma-ray units are presented showing a resolution in CT of 3.2 mm-1 at a radial distance of 50 mm from the rotation axis and that the 5 and 8 mm hot masses (99mTc labeled with a 15:1 activity ratio with respect to the background) can be detected in planar gamma-ray imaging with a contrast-to-noise ratio of about 4.
AB - We describe the design, realization and basic tests of a prototype Cone-Beam Breast Computed Tomography (CBBCT) scanner, combined with a SPECT head consisting of a compact pinhole gamma camera based on a photon counting CdTe hybrid pixel detector. The instrument features a 40 μm focal spot X-ray tube, a 50 μm pitch flat panel detector and a 1-mm-thick, 55 μm pitch CdTe pixel detector. Preliminary imaging tests of the separate CT and gamma-ray units are presented showing a resolution in CT of 3.2 mm-1 at a radial distance of 50 mm from the rotation axis and that the 5 and 8 mm hot masses (99mTc labeled with a 15:1 activity ratio with respect to the background) can be detected in planar gamma-ray imaging with a contrast-to-noise ratio of about 4.
KW - Breast computed tomographySPECT/CT multimodality imaging
UR - http://www.scopus.com/inward/record.url?scp=79251635186&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79251635186&partnerID=8YFLogxK
U2 - 10.1016/j.nima.2010.10.093
DO - 10.1016/j.nima.2010.10.093
M3 - Article
VL - 629
SP - 350
EP - 356
JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
SN - 0168-9002
IS - 1
ER -