TY - JOUR
T1 - Dedicated scanner for laboratory investigations on cone-beam CT/SPECT imaging of the breast
AU - Mettivier, Giovanni
AU - Russo, Paolo
AU - Cesarelli, Mario
AU - Ospizio, Roberto
AU - Passeggio, Giuseppe
AU - Roscilli, Lorenzo
AU - Pontoriere, Giuseppe
AU - Rocco, Raffaele
PY - 2011/2/11
Y1 - 2011/2/11
N2 - We describe the design, realization and basic tests of a prototype Cone-Beam Breast Computed Tomography (CBBCT) scanner, combined with a SPECT head consisting of a compact pinhole gamma camera based on a photon counting CdTe hybrid pixel detector. The instrument features a 40 μm focal spot X-ray tube, a 50 μm pitch flat panel detector and a 1-mm-thick, 55 μm pitch CdTe pixel detector. Preliminary imaging tests of the separate CT and gamma-ray units are presented showing a resolution in CT of 3.2 mm-1 at a radial distance of 50 mm from the rotation axis and that the 5 and 8 mm hot masses (99mTc labeled with a 15:1 activity ratio with respect to the background) can be detected in planar gamma-ray imaging with a contrast-to-noise ratio of about 4.
AB - We describe the design, realization and basic tests of a prototype Cone-Beam Breast Computed Tomography (CBBCT) scanner, combined with a SPECT head consisting of a compact pinhole gamma camera based on a photon counting CdTe hybrid pixel detector. The instrument features a 40 μm focal spot X-ray tube, a 50 μm pitch flat panel detector and a 1-mm-thick, 55 μm pitch CdTe pixel detector. Preliminary imaging tests of the separate CT and gamma-ray units are presented showing a resolution in CT of 3.2 mm-1 at a radial distance of 50 mm from the rotation axis and that the 5 and 8 mm hot masses (99mTc labeled with a 15:1 activity ratio with respect to the background) can be detected in planar gamma-ray imaging with a contrast-to-noise ratio of about 4.
KW - Breast computed tomographySPECT/CT multimodality imaging
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U2 - 10.1016/j.nima.2010.10.093
DO - 10.1016/j.nima.2010.10.093
M3 - Article
AN - SCOPUS:79251635186
VL - 629
SP - 350
EP - 356
JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
SN - 0168-9002
IS - 1
ER -