Dedicated scanner for laboratory investigations on cone-beam CT/SPECT imaging of the breast

Giovanni Mettivier; Paolo Russo; Mario Cesarelli; Roberto Ospizio; Giuseppe Passeggio; Lorenzo Roscilli; Giuseppe Pontoriere; Raffaele Rocco

doi:10.1016/j.nima.2010.10.093

Dedicated scanner for laboratory investigations on cone-beam CT/SPECT imaging of the breast

Giovanni Mettivier, Paolo Russo, Mario Cesarelli, Roberto Ospizio, Giuseppe Passeggio, Lorenzo Roscilli, Giuseppe Pontoriere, Raffaele Rocco

Istituti Clinici Scientifici Maugeri Spa – Società Benefit

Research output: Contribution to journal › Article › peer-review

Abstract

We describe the design, realization and basic tests of a prototype Cone-Beam Breast Computed Tomography (CBBCT) scanner, combined with a SPECT head consisting of a compact pinhole gamma camera based on a photon counting CdTe hybrid pixel detector. The instrument features a 40 μm focal spot X-ray tube, a 50 μm pitch flat panel detector and a 1-mm-thick, 55 μm pitch CdTe pixel detector. Preliminary imaging tests of the separate CT and gamma-ray units are presented showing a resolution in CT of 3.2 mm^-1 at a radial distance of 50 mm from the rotation axis and that the 5 and 8 mm hot masses (^99mTc labeled with a 15:1 activity ratio with respect to the background) can be detected in planar gamma-ray imaging with a contrast-to-noise ratio of about 4.

Original language	English
Pages (from-to)	350-356
Number of pages	7
Journal	Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume	629
Issue number	1
DOIs	https://doi.org/10.1016/j.nima.2010.10.093
Publication status	Published - Feb 11 2011

Keywords

Breast computed tomographySPECT/CT multimodality imaging

ASJC Scopus subject areas

Instrumentation
Nuclear and High Energy Physics

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Mettivier, G., Russo, P., Cesarelli, M., Ospizio, R., Passeggio, G., Roscilli, L., Pontoriere, G., & Rocco, R. (2011). Dedicated scanner for laboratory investigations on cone-beam CT/SPECT imaging of the breast. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 629(1), 350-356. https://doi.org/10.1016/j.nima.2010.10.093

Dedicated scanner for laboratory investigations on cone-beam CT/SPECT imaging of the breast. / Mettivier, Giovanni; Russo, Paolo; Cesarelli, Mario; Ospizio, Roberto; Passeggio, Giuseppe; Roscilli, Lorenzo; Pontoriere, Giuseppe; Rocco, Raffaele.

In: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 629, No. 1, 11.02.2011, p. 350-356.

Research output: Contribution to journal › Article › peer-review

Mettivier, G, Russo, P, Cesarelli, M, Ospizio, R, Passeggio, G, Roscilli, L, Pontoriere, G & Rocco, R 2011, 'Dedicated scanner for laboratory investigations on cone-beam CT/SPECT imaging of the breast', Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, vol. 629, no. 1, pp. 350-356. https://doi.org/10.1016/j.nima.2010.10.093

Mettivier, Giovanni ; Russo, Paolo ; Cesarelli, Mario ; Ospizio, Roberto ; Passeggio, Giuseppe ; Roscilli, Lorenzo ; Pontoriere, Giuseppe ; Rocco, Raffaele. / Dedicated scanner for laboratory investigations on cone-beam CT/SPECT imaging of the breast. In: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2011 ; Vol. 629, No. 1. pp. 350-356.

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