Dedifferentiated chondrosarcoma

R. Capanna, F. Bertoni, G. Bettelli, P. Picci, P. Bacchini, D. Present, A. Giunti, M. Campanacci

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The cases of forty-six patients who had dedifferentiated chondrosarcoma were reviewed. Two groups were identified: one in which a low-grade malignant chondrosarcoma was the precursor lesion and one in which a moderate to high-grade malignant chondrosarcoma was the precursor lesion. The radiographic features of these lesions ranged from that of a cartilaginous lesion that appeared to be benign to that of a destructive osteolytic tumor in which the cartilaginous component was overshadowed by the dedifferentiated component. Only three of the forty-six patients survived for more than two years. Resection alone, even when it was wide or radical, was not successful in controlling this lethal sarcoma.

Original languageEnglish
Pages (from-to)60-69
Number of pages10
JournalJournal of Bone and Joint Surgery - Series A
Issue number1
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery


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