Dedifferentiated chondrosarcoma with "adamantinoma-like" features: A case report and review of literature

Marco Gambarotti, Alberto Righi, Tommaso Frisoni, Davide Maria Donati, Daniel Vanel, Marta Sbaraglia, Angelo P. Dei Tos

Research output: Contribution to journal › Article

2 Citations (Scopus)

Abstract

Dedifferentiated chondrosarcoma is defined by the presence of a low grade malignant cartilaginous component juxtaposed to a high grade malignant non-cartilaginous sarcomatous components. Only 4 cases in which the high grade component showed epithelial differentiation have been reported in the literature; three featured a squamous and the one a glandular epithelial component. Here we describe a case of dedifferentiated chondrosarcoma exhibiting epithelial "adamantinoma-like" basaloid features. The patient underwent wide resection of the proximal tibia and post-operative chemotherapy and died 8 months after the diagnosis due to lung and bone metastases.
Original languageEnglish
Pages (from-to)698-701
Number of pages4
JournalPathology Research and Practice
Volume213
Issue number6
DOIs
Publication statusPublished - May 6 2017

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Adamantinoma
Chondrosarcoma
Tibia
Neoplasm Metastasis
Bone and Bones
Drug Therapy
Lung

Keywords

  • Adamantinoma-like
  • Basaloid
  • Dedifferentiated chondrosarcoma
  • Epithelial

Cite this

Dedifferentiated chondrosarcoma with "adamantinoma-like" features: A case report and review of literature. / Gambarotti, Marco; Righi, Alberto; Frisoni, Tommaso; Donati, Davide Maria; Vanel, Daniel; Sbaraglia, Marta; Dei Tos, Angelo P.

In: Pathology Research and Practice, Vol. 213, No. 6, 06.05.2017, p. 698-701.

Research output: Contribution to journal › Article

Gambarotti, M, Righi, A, Frisoni, T, Donati, DM, Vanel, D, Sbaraglia, M & Dei Tos, AP 2017, 'Dedifferentiated chondrosarcoma with "adamantinoma-like" features: A case report and review of literature', Pathology Research and Practice, vol. 213, no. 6, pp. 698-701. https://doi.org/10.1016/j.prp.2017.04.019
Gambarotti M, Righi A, Frisoni T, Donati DM, Vanel D, Sbaraglia M et al. Dedifferentiated chondrosarcoma with "adamantinoma-like" features: A case report and review of literature. Pathology Research and Practice. 2017 May 6;213(6):698-701. https://doi.org/10.1016/j.prp.2017.04.019
Gambarotti, Marco ; Righi, Alberto ; Frisoni, Tommaso ; Donati, Davide Maria ; Vanel, Daniel ; Sbaraglia, Marta ; Dei Tos, Angelo P. / Dedifferentiated chondrosarcoma with "adamantinoma-like" features: A case report and review of literature. In: Pathology Research and Practice. 2017 ; Vol. 213, No. 6. pp. 698-701.
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AU - Vanel, Daniel

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AU - Dei Tos, Angelo P.

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