Dedifferentiated chondrosarcoma with "adamantinoma-like" features: A case report and review of literature

Marco Gambarotti, Alberto Righi, Tommaso Frisoni, Davide Maria Donati, Daniel Vanel, Marta Sbaraglia, Angelo P. Dei Tos

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Dedifferentiated chondrosarcoma is defined by the presence of a low grade malignant cartilaginous component juxtaposed to a high grade malignant non-cartilaginous sarcomatous components. Only 4 cases in which the high grade component showed epithelial differentiation have been reported in the literature; three featured a squamous and the one a glandular epithelial component. Here we describe a case of dedifferentiated chondrosarcoma exhibiting epithelial "adamantinoma-like" basaloid features. The patient underwent wide resection of the proximal tibia and post-operative chemotherapy and died 8 months after the diagnosis due to lung and bone metastases.
Original languageEnglish
Pages (from-to)698-701
Number of pages4
JournalPathology Research and Practice
Volume213
Issue number6
DOIs
Publication statusPublished - May 6 2017

Fingerprint

Adamantinoma
Chondrosarcoma
Tibia
Neoplasm Metastasis
Bone and Bones
Drug Therapy
Lung

Keywords

  • Adamantinoma-like
  • Basaloid
  • Dedifferentiated chondrosarcoma
  • Epithelial

Cite this

Dedifferentiated chondrosarcoma with "adamantinoma-like" features: A case report and review of literature. / Gambarotti, Marco; Righi, Alberto; Frisoni, Tommaso; Donati, Davide Maria; Vanel, Daniel; Sbaraglia, Marta; Dei Tos, Angelo P.

In: Pathology Research and Practice, Vol. 213, No. 6, 06.05.2017, p. 698-701.

Research output: Contribution to journalArticle

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AU - Sbaraglia, Marta

AU - Dei Tos, Angelo P.

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