Dedifferentiated chondrosarcoma with "adamantinoma-like" features: A case report and review of literature

Marco Gambarotti; Alberto Righi; Tommaso Frisoni; Davide Maria Donati; Daniel Vanel; Marta Sbaraglia; Angelo P. Dei Tos

doi:10.1016/j.prp.2017.04.019

Dedifferentiated chondrosarcoma with "adamantinoma-like" features: A case report and review of literature

Marco Gambarotti, Alberto Righi, Tommaso Frisoni, Davide Maria Donati, Daniel Vanel, Marta Sbaraglia, Angelo P. Dei Tos

Istituti Ortopedici Rizzoli

Research output: Contribution to journal › Article › peer-review

Abstract

Dedifferentiated chondrosarcoma is defined by the presence of a low grade malignant cartilaginous component juxtaposed to a high grade malignant non-cartilaginous sarcomatous components. Only 4 cases in which the high grade component showed epithelial differentiation have been reported in the literature; three featured a squamous and the one a glandular epithelial component. Here we describe a case of dedifferentiated chondrosarcoma exhibiting epithelial "adamantinoma-like" basaloid features. The patient underwent wide resection of the proximal tibia and post-operative chemotherapy and died 8 months after the diagnosis due to lung and bone metastases.

Original language	English
Pages (from-to)	698-701
Number of pages	4
Journal	Pathology Research and Practice
Volume	213
Issue number	6
DOIs	https://doi.org/10.1016/j.prp.2017.04.019
Publication status	Published - May 6 2017

Keywords

Adamantinoma-like
Basaloid
Dedifferentiated chondrosarcoma
Epithelial

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Dedifferentiated chondrosarcoma with "adamantinoma-like" features: A case report and review of literature. / Gambarotti, Marco ; Righi, Alberto; Frisoni, Tommaso; Donati, Davide Maria; Vanel, Daniel; Sbaraglia, Marta; Dei Tos, Angelo P.

In: Pathology Research and Practice, Vol. 213, No. 6, 06.05.2017, p. 698-701.

Research output: Contribution to journal › Article › peer-review

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AU - Dei Tos, Angelo P.

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