Deep brain stimulation and headache

Giovanni Broggi, Giuseppe Messina, Roberto Cordella, Ivano Dones, Angelo Franzini

Research output: Chapter in Book/Report/Conference proceedingChapter


The posterior hypothalamus is being considered a valid target for deep brain stimulation (DBS) in trigeminal autonomic cephalalgias in selected patients. Its main afferent structures include: amygdala, hippocampus, septal nuclei, orbital cortex and retina. Its main efferent structures include: anterior nucleus of the thalamus, overall cerebral cortex through histaminergic projections, amygdala, hippocampus, septal nuclei and midbrain reticular formation. Such connections are thought to be the key issue in the therapeutic efficacy of its high-frequency stimulation.

Original languageEnglish
Title of host publicationDeep Brain Stimulation: Technology and Applications
PublisherFuture Medicine Ltd.
Number of pages2
ISBN (Print)9781780845319, 9781780845333
Publication statusPublished - Aug 1 2014

ASJC Scopus subject areas

  • Medicine(all)


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