Deep brain stimulation (DBS) attentional effects parallel those of l-dopa treatment.

L. Brusa, M. Pierantozzi, A. Peppe, M. G. Altibrandi, P. Giacomini, P. Mazzone, P. Stanzione

Research output: Contribution to journalArticle

Abstract

Aim of our study was to investigate the different effects on attentional capacity of deep brain stimulation DBS (STN or GPi) and of l-dopa in PD patients. Patients were evaluated on-DBS/off-l-dopa, on-l-dopa/off-DBS, on-l-dopa/on-DBS and off-l-dopa/off-DBS. Our results indicate that DBS effects on attentional functions parallel those of l-dopa. A site independent (both STN and GPi) worsening of verbal fluency was observed, possibly connected to the stimulus effect on the cortico-subcortical-cortical loop.

Original languageEnglish
Pages (from-to)1021-1027
Number of pages7
JournalJournal of Neural Transmission
Volume108
Issue number8-9
DOIs
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Deep brain stimulation (DBS) attentional effects parallel those of l-dopa treatment.'. Together they form a unique fingerprint.

  • Cite this

    Brusa, L., Pierantozzi, M., Peppe, A., Altibrandi, M. G., Giacomini, P., Mazzone, P., & Stanzione, P. (2001). Deep brain stimulation (DBS) attentional effects parallel those of l-dopa treatment. Journal of Neural Transmission, 108(8-9), 1021-1027. https://doi.org/10.1007/s007020170020