Deep brain stimulation for aggressive behavior and obsessive-compulsive disorder

Giuseppe Messina, Lucrezia Islam, Roberto Cordella, Orsola Gambini, Angelo Franzini

Research output: Contribution to journalReview articlepeer-review


Drug-resistant obsessive-compulsive disorder and aggressive behavior are two severely disabling psychiatric conditions which may carry a certain burden on the patients themselves and on their families. In the last decade, the ields of interests of deep brain stimulation (DBS) also encompass psychiatric disorders, supported by imaging and neurophysiological techniques. We here report our institutional experience with the two above-mentioned disorders, describing the procedure commonly employed and the results obtained. Reinement of such techniques, possibly relying on advanced magnetic resonance imaging (MRI), together with probabilistic pictures of ield of activation models, could shed more light into this complex ield of investigation; further studies are necessary to conirm and make actual results a starting point to new and more precise methodologies in this stimulating research ield.

Original languageEnglish
Pages (from-to)211-217
Number of pages7
JournalJournal of Neurosurgical Sciences
Issue number2
Publication statusPublished - 2016


  • Aggression
  • Deep brain stimulation
  • Obsessive-compulsive disorder

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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