TY - JOUR
T1 - Deep brain stimulation for the treatment of Parkinson's disease
T2 - The experience of the neurosurgical department of Monza
AU - Landi, A.
AU - Parolin, M.
AU - Piolti, R.
AU - Antonini, A.
AU - Grimaldi, M.
AU - Crespi, M.
AU - Iurlaro, S.
AU - Aliprandi, A.
AU - Pezzoli, G.
AU - Ferrarese, C.
AU - Gaini, S. M.
PY - 2003/5
Y1 - 2003/5
N2 - Deep brain stimulation is a widely accepted surgical therapy for the symptomatic treatment of advanced parkinson's disease; high frequency chronic stimulation of the subthalamic nucleus proved its efficacy to control the major motor symptoms. In the neurosurgical department of Monza we treated 72 parkinsonian patients (November 1998-January 2003). One year follow-up results are: decrease of tremor 90%, hypertonous 56%, bradykinesia 70%, voice impairment amelioration 30%, mean total daily L-dopa intake reduced 58%. Freezing and balance did not ameliorate, some voice impairment and psychic derangement have been observed. Major surgical complications were: haemorrage (1 case - transient hemiparesis), infections (2 cases), pulmonary embolisation (1 case). To optimise the surgical results, careful clinical and instrumental selection of the patients are mandatory before surgery.
AB - Deep brain stimulation is a widely accepted surgical therapy for the symptomatic treatment of advanced parkinson's disease; high frequency chronic stimulation of the subthalamic nucleus proved its efficacy to control the major motor symptoms. In the neurosurgical department of Monza we treated 72 parkinsonian patients (November 1998-January 2003). One year follow-up results are: decrease of tremor 90%, hypertonous 56%, bradykinesia 70%, voice impairment amelioration 30%, mean total daily L-dopa intake reduced 58%. Freezing and balance did not ameliorate, some voice impairment and psychic derangement have been observed. Major surgical complications were: haemorrage (1 case - transient hemiparesis), infections (2 cases), pulmonary embolisation (1 case). To optimise the surgical results, careful clinical and instrumental selection of the patients are mandatory before surgery.
KW - Complications
KW - Deep brain stimulation
KW - Parkinson's disease
KW - Results
UR - http://www.scopus.com/inward/record.url?scp=18544410037&partnerID=8YFLogxK
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U2 - 10.1007/s100720300039
DO - 10.1007/s100720300039
M3 - Article
C2 - 12774214
AN - SCOPUS:18544410037
VL - 24
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - SUPPL. 1
ER -