Deep brain stimulation in myoclonus-dystonia syndrome

Laura Cif; Enza Maria Valente; Simone Hemm; Christine Coubes; Nathalie Vayssiere; Stéphanie Serrat; Annalisa Di Giorgio; Philippe Coubes

doi:10.1002/mds.20030

Deep brain stimulation in myoclonus-dystonia syndrome

Laura Cif, Enza Maria Valente, Simone Hemm, Christine Coubes, Nathalie Vayssiere, Stéphanie Serrat, Annalisa Di Giorgio, Philippe Coubes

IRCCS Casa Sollievo della Sofferenza

Research output: Contribution to journal › Article › peer-review

Abstract

Myoclonus-dystonia syndrome (MDS) is an autosomal dominant disorder characterized by bilateral myoclonic jerks. An 8-year-old boy presenting with early onset, medically intractable, MDS due to a mutation in the ε-sarcoglycan gene (SGCE) underwent chronic bilateral stimulation of the globus pallidus internus, which eliminates both myoclonus and dystonia. We conclude that deep brain stimulation can be an effective and safe treatment for MDS.

Original language	English
Pages (from-to)	724-727
Number of pages	4
Journal	Movement Disorders
Volume	19
Issue number	6
DOIs	https://doi.org/10.1002/mds.20030
Publication status	Published - Jun 2004

Keywords

Dystonia
Myoclonus
Neurosurgery

ASJC Scopus subject areas

Clinical Neurology
Neuroscience(all)

Access to Document

10.1002/mds.20030

Cite this

@article{0ab0500e0b2443c3a4df29e8015749f8,

title = "Deep brain stimulation in myoclonus-dystonia syndrome",

abstract = "Myoclonus-dystonia syndrome (MDS) is an autosomal dominant disorder characterized by bilateral myoclonic jerks. An 8-year-old boy presenting with early onset, medically intractable, MDS due to a mutation in the ε-sarcoglycan gene (SGCE) underwent chronic bilateral stimulation of the globus pallidus internus, which eliminates both myoclonus and dystonia. We conclude that deep brain stimulation can be an effective and safe treatment for MDS.",

keywords = "Dystonia, Myoclonus, Neurosurgery",

author = "Laura Cif and Valente, {Enza Maria} and Simone Hemm and Christine Coubes and Nathalie Vayssiere and St{\'e}phanie Serrat and {Di Giorgio}, Annalisa and Philippe Coubes",

year = "2004",

month = jun,

doi = "10.1002/mds.20030",

language = "English",

volume = "19",

pages = "724--727",

journal = "Movement Disorders",

issn = "0885-3185",

publisher = "John Wiley and Sons Inc.",

number = "6",

}

TY - JOUR

T1 - Deep brain stimulation in myoclonus-dystonia syndrome

AU - Cif, Laura

AU - Valente, Enza Maria

AU - Hemm, Simone

AU - Coubes, Christine

AU - Vayssiere, Nathalie

AU - Serrat, Stéphanie

AU - Di Giorgio, Annalisa

AU - Coubes, Philippe

PY - 2004/6

Y1 - 2004/6

N2 - Myoclonus-dystonia syndrome (MDS) is an autosomal dominant disorder characterized by bilateral myoclonic jerks. An 8-year-old boy presenting with early onset, medically intractable, MDS due to a mutation in the ε-sarcoglycan gene (SGCE) underwent chronic bilateral stimulation of the globus pallidus internus, which eliminates both myoclonus and dystonia. We conclude that deep brain stimulation can be an effective and safe treatment for MDS.

AB - Myoclonus-dystonia syndrome (MDS) is an autosomal dominant disorder characterized by bilateral myoclonic jerks. An 8-year-old boy presenting with early onset, medically intractable, MDS due to a mutation in the ε-sarcoglycan gene (SGCE) underwent chronic bilateral stimulation of the globus pallidus internus, which eliminates both myoclonus and dystonia. We conclude that deep brain stimulation can be an effective and safe treatment for MDS.

KW - Dystonia

KW - Myoclonus

KW - Neurosurgery

UR - http://www.scopus.com/inward/record.url?scp=4444366151&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4444366151&partnerID=8YFLogxK

U2 - 10.1002/mds.20030

DO - 10.1002/mds.20030

M3 - Article

C2 - 15197720

AN - SCOPUS:4444366151

VL - 19

SP - 724

EP - 727

JO - Movement Disorders

JF - Movement Disorders

SN - 0885-3185

IS - 6

ER -

Deep brain stimulation in myoclonus-dystonia syndrome

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this