Deep brain stimulation of CM/PF of thalamus could be the new elective target for tremor in advanced Parkinson's Disease?

A. Peppe; A. Gasbarra; A. Stefani; C. Chiavalon; M. Pierantozzi; E. Fermi; P. Stanzione; C. Caltagirone; P. Mazzone

doi:10.1016/j.parkreldis.2007.11.005

Deep brain stimulation of CM/PF of thalamus could be the new elective target for tremor in advanced Parkinson's Disease?

A. Peppe, A. Gasbarra, A. Stefani, C. Chiavalon, M. Pierantozzi, E. Fermi, P. Stanzione, C. Caltagirone, P. Mazzone

Fondazione Santa Lucia

Research output: Contribution to journal › Article › peer-review

Abstract

Aim of this study was to investigate whether Deep Brain Stimulation (DBS) of the Centre Median Nucleus/Parafascicular (CM/PF) Complex is useful in reducing extrapyramidal symptoms in advanced Parkinson's Disease (PD) patients. In particular, we compared the action of CM/PF and subthalamic nucleus (STN) DBS on resting hand tremor using EMG surface of ulnar and radial right-hand muscles. Our results show that C/M DBS is very effective in reducing tremor, indicating this complex as a new target in advanced PD patients.

Original language	English
Pages (from-to)	501-504
Number of pages	4
Journal	Parkinsonism and Related Disorders
Volume	14
Issue number	6
DOIs	https://doi.org/10.1016/j.parkreldis.2007.11.005
Publication status	Published - Aug 2008

Keywords

CM/PF complex
DBS
Parkinson Disease
Surface EMG
Tremor

ASJC Scopus subject areas

Ageing
Clinical Neurology
Neurology

Access to Document

10.1016/j.parkreldis.2007.11.005

Cite this

@article{45b326ccca634aecad00ff617039cf1c,

title = "Deep brain stimulation of CM/PF of thalamus could be the new elective target for tremor in advanced Parkinson's Disease?",

abstract = "Aim of this study was to investigate whether Deep Brain Stimulation (DBS) of the Centre Median Nucleus/Parafascicular (CM/PF) Complex is useful in reducing extrapyramidal symptoms in advanced Parkinson's Disease (PD) patients. In particular, we compared the action of CM/PF and subthalamic nucleus (STN) DBS on resting hand tremor using EMG surface of ulnar and radial right-hand muscles. Our results show that C/M DBS is very effective in reducing tremor, indicating this complex as a new target in advanced PD patients.",

keywords = "CM/PF complex, DBS, Parkinson Disease, Surface EMG, Tremor",

author = "A. Peppe and A. Gasbarra and A. Stefani and C. Chiavalon and M. Pierantozzi and E. Fermi and P. Stanzione and C. Caltagirone and P. Mazzone",

year = "2008",

month = aug,

doi = "10.1016/j.parkreldis.2007.11.005",

language = "English",

volume = "14",

pages = "501--504",

journal = "Parkinsonism and Related Disorders",

issn = "1353-8020",