Deep brain stimulation of CM/PF of thalamus could be the new elective target for tremor in advanced Parkinson's Disease?

A. Peppe, A. Gasbarra, A. Stefani, C. Chiavalon, M. Pierantozzi, E. Fermi, P. Stanzione, C. Caltagirone, P. Mazzone

Research output: Contribution to journalArticlepeer-review

Abstract

Aim of this study was to investigate whether Deep Brain Stimulation (DBS) of the Centre Median Nucleus/Parafascicular (CM/PF) Complex is useful in reducing extrapyramidal symptoms in advanced Parkinson's Disease (PD) patients. In particular, we compared the action of CM/PF and subthalamic nucleus (STN) DBS on resting hand tremor using EMG surface of ulnar and radial right-hand muscles. Our results show that C/M DBS is very effective in reducing tremor, indicating this complex as a new target in advanced PD patients.

Original languageEnglish
Pages (from-to)501-504
Number of pages4
JournalParkinsonism and Related Disorders
Volume14
Issue number6
DOIs
Publication statusPublished - Aug 2008

Keywords

  • CM/PF complex
  • DBS
  • Parkinson Disease
  • Surface EMG
  • Tremor

ASJC Scopus subject areas

  • Ageing
  • Clinical Neurology
  • Neurology

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