Abstract
Introduction Deep brain stimulation (DBS) has been proposed for the treatment of severe and refractory major depressive disorder, including DBS of Broadman's area 25 (BA 25 subgenual cortex). Report We report DBS of this cerebral region in a patient affected by long-lasting disabling and drug-resistant bipolar disorder previously submitted to electroconvulsive therapy (ECT) and vagal nerve stimulation (VNS). Results After the procedure and at 2.5 years follow-up the patient presented substantial improvement of depressive symptoms and maintained a stable drug therapy regimen Discussion Our results suggest a possible therapeutic role for BA 25 DBS even in patients affected by bipolar disorder previously treated by ECT and VNS.
| Original language | English |
|---|---|
| Pages (from-to) | 93-96 |
| Number of pages | 4 |
| Journal | Italian Journal of Psychopathology |
| Volume | 21 |
| Issue number | 1 |
| Publication status | Published - Mar 1 2015 |
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Keywords
- Bipolar disorder
- Deep brain stimulation
- Major depression
ASJC Scopus subject areas
- Psychiatry and Mental health
- Clinical Psychology
Cite this
Deep brain stimulation of the subgenual cortex for treatment of refractory bipolar disorder : Case report and literature review. / Messina, G.; Rizzi, M.; Cordella, R.; Castiglione, M.; Gambini, O.; Franzini, A.
In: Italian Journal of Psychopathology, Vol. 21, No. 1, 01.03.2015, p. 93-96.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Deep brain stimulation of the subgenual cortex for treatment of refractory bipolar disorder
T2 - Case report and literature review
AU - Messina, G.
AU - Rizzi, M.
AU - Cordella, R.
AU - Castiglione, M.
AU - Gambini, O.
AU - Franzini, A.
PY - 2015/3/1
Y1 - 2015/3/1
N2 - Introduction Deep brain stimulation (DBS) has been proposed for the treatment of severe and refractory major depressive disorder, including DBS of Broadman's area 25 (BA 25 subgenual cortex). Report We report DBS of this cerebral region in a patient affected by long-lasting disabling and drug-resistant bipolar disorder previously submitted to electroconvulsive therapy (ECT) and vagal nerve stimulation (VNS). Results After the procedure and at 2.5 years follow-up the patient presented substantial improvement of depressive symptoms and maintained a stable drug therapy regimen Discussion Our results suggest a possible therapeutic role for BA 25 DBS even in patients affected by bipolar disorder previously treated by ECT and VNS.
AB - Introduction Deep brain stimulation (DBS) has been proposed for the treatment of severe and refractory major depressive disorder, including DBS of Broadman's area 25 (BA 25 subgenual cortex). Report We report DBS of this cerebral region in a patient affected by long-lasting disabling and drug-resistant bipolar disorder previously submitted to electroconvulsive therapy (ECT) and vagal nerve stimulation (VNS). Results After the procedure and at 2.5 years follow-up the patient presented substantial improvement of depressive symptoms and maintained a stable drug therapy regimen Discussion Our results suggest a possible therapeutic role for BA 25 DBS even in patients affected by bipolar disorder previously treated by ECT and VNS.
KW - Bipolar disorder
KW - Deep brain stimulation
KW - Major depression
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UR - http://www.scopus.com/inward/citedby.url?scp=84947933098&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:84947933098
VL - 21
SP - 93
EP - 96
JO - Giornale Italiano di Psicopatologia
JF - Giornale Italiano di Psicopatologia
SN - 1592-1107
IS - 1
ER -