Deep brain stimulation to relieve drug-resistant SUNCT

Massimo Leone, Angelo Franzini, Giovanni D'Andrea, Giovanni Broggi, Gerardo Casucci, Gennaro Bussone

Research output: Contribution to journalArticlepeer-review


The rare primary headache short-lasting unilateral neuralgiform headache attacks with conjunctiva! injection and tearing (SUNCT) is characterized by 3 to 200 attacks per day of severe unilateral orbital pain. Functional magnetic resonance imaging shows increased blood flow in the ipsilateral posterior inferior hypothalamus during attacks, indicating activation. We report the first patient with SUNCT in whom severe intractable pain (70 per day) was well controlled by electrode implant to and continuous stimulation of the posterior inferior hypothalamus.

Original languageEnglish
Pages (from-to)924-927
Number of pages4
JournalAnnals of Neurology
Issue number6
Publication statusPublished - Jun 2005

ASJC Scopus subject areas

  • Neuroscience(all)


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