Deep Transcranial Magnetic Stimulation for treatment-resistant bipolar depression: A case report of acute and maintenance efficacy

Francesco Saverio Bersani, Nicoletta Girardi, Livia Sanna, Lorenzo Mazzarini, Chiara Santucci, Giorgio D. Kotzalidis, Gabriele Sani, Pietro De Rossi, Ruggero N. Raccah, Saverio Simone Caltagirone, Mariella Battipaglia, Silvia Capezzuto, Giuseppe Bersani, Paolo Girardi

Research output: Contribution to journalArticle

Abstract

Deep Transcranial Magnetic Stimulation (dTMS) is currently being evaluated as a possible treatment for several neuropsychiatric disorders and has been demonstrated as a safe and effective procedure. This case presents a patient with bipolar depression that has been treated with 20 daily consecutive dTMS sessions and with one dTMS session every 2 weeks for the following 3 months. Depressive symptoms improved rapidly and response was maintained during the next 6 months; cognitive performances also improved. This report suggests that add-on dTMS may help overcoming drug-resistance in bipolar depression and protect from subsequent bipolar episodes of any polarity.

Original languageEnglish
Pages (from-to)451-457
Number of pages7
JournalNeurocase
Volume19
Issue number5
DOIs
Publication statusPublished - Oct 2013

Keywords

  • Bipolar depression
  • Deep Transcranial Magnetic Stimulation
  • Maintenance treatment of bipolar disorder
  • Prefrontal cortex
  • Treatment-resistant bipolar disorder

ASJC Scopus subject areas

  • Clinical Neurology
  • Arts and Humanities (miscellaneous)

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  • Cite this

    Bersani, F. S., Girardi, N., Sanna, L., Mazzarini, L., Santucci, C., Kotzalidis, G. D., Sani, G., De Rossi, P., Raccah, R. N., Caltagirone, S. S., Battipaglia, M., Capezzuto, S., Bersani, G., & Girardi, P. (2013). Deep Transcranial Magnetic Stimulation for treatment-resistant bipolar depression: A case report of acute and maintenance efficacy. Neurocase, 19(5), 451-457. https://doi.org/10.1080/13554794.2012.690429