Deep-vein thrombosis of the lower limbs: Diagnosis and management

Paolo Prandoni, Pier Mannuccio Mannucci

Research output: Contribution to journalArticlepeer-review


Acute deep venous thrombosis (DVT) of the lower extremities is a serious and potentially fatal disorder which often complicates the course of severely ill, hospitalized patients but may also affect ambulatory and otherwise healthy people. It is uncommon in young individuals and becomes more frequent with advancing age. The clinically important problems associated with DVT are death from pulmonary embolism (PE), morbidity resulting from the acute event, the post-thrombotic syndrome, and the inconvenience and side-effects of investigations and treatment. Furthermore, an often underemphasized problem is the anxiety that may occur in those patients who have suffered a thrombotic episode.

Original languageEnglish
Pages (from-to)533-554
Number of pages22
JournalBest Practice and Research: Clinical Haematology
Issue number3
Publication statusPublished - Sep 1999


  • Deep-vein thrombosis
  • Low-molecular-weight heparin
  • Oral anticoagulants
  • Thrombophilic state
  • Venous thromboembolism

ASJC Scopus subject areas

  • Cancer Research
  • Oncology


Dive into the research topics of 'Deep-vein thrombosis of the lower limbs: Diagnosis and management'. Together they form a unique fingerprint.

Cite this