DEFB1 gene polymorphisms and increased risk of HIV-1 infection in Brazilian children

Michele Milanese, Ludovica Segat, Alessandra Pontillo, Luiz Claudio Arraes, José Luiz De Lima Filho, Sergio Crovella

Research output: Contribution to journalArticle


In our study we analysed three single nucleotide polymorphisms (SNPs) in the 5′ untranslated region (UTR) of the DEFB1 gene, namely -52(G/A) -44(C/G) and -20(G/A), in three groups of northeastern Brazilian children in order to assess their role in HIV-1 infection. Our results allowed us to hypothesize that the SNPs located in the 5′ UTR of the DEFB1 gene can be employed as a marker of risk for HIV-1 infection.

Original languageEnglish
Pages (from-to)1673-1675
Number of pages3
JournalAIDS (London, England)
Issue number12
Publication statusPublished - Aug 2006


ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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