Defective interaction of mutant calreticulin and SOCE in megakaryocytes from patients with myeloproliferative neoplasms

C.A. Di Buduo, V. Abbonante, C. Marty, F. Moccia, E. Rumi, D. Pietra, P.M. Soprano, D. Lim, D. Cattaneo, A. Iurlo, U. Gianelli, G. Barosi, V. Rosti, I. Plo, M. Cazzola, A. Balduini

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)133-144
Number of pages12
JournalBlood
Volume135
Issue number2
DOIs
Publication statusPublished - 2020

Keywords

  • calcium
  • calreticulin
  • endoplasmic reticulum protein 57
  • inositol trisphosphate
  • mitogen activated protein kinase 1
  • mitogen activated protein kinase 3
  • STAT5 protein
  • stromal interaction molecule 1
  • thrombopoietin
  • unclassified drug
  • Article
  • calcium cell level
  • calcium mobilization
  • cell proliferation
  • endoplasmic reticulum
  • enzyme linked immunosorbent assay
  • extracellular calcium
  • gene mutation
  • human
  • human cell
  • intracellular signaling
  • megakaryocyte
  • myeloproliferative neoplasm
  • pathophysiology
  • phenotype
  • priority journal
  • somatic mutation
  • store operated calcium entry
  • Western blotting

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